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线性分子式:
ClC6H4CO2H
化学文摘社编号:
分子量:
156.57
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-618-4
Beilstein/REAXYS Number:
907218
MDL number:
产品名称
3-氯苯甲酸, Pharmaceutical Secondary Standard; Certified Reference Material
SMILES string
OC(=O)c1cccc(Cl)c1
InChI
1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)
InChI key
LULAYUGMBFYYEX-UHFFFAOYSA-N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1112299
API family
bupropion
CofA
current certificate can be downloaded
packaging
pkg of 200 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
153-157 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
3-Chlorobenzoic acid may be used as a pharmaceutical reference standard for the determination of the analyte in bulk powders and pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7967 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
Kinetic study and peak purity determination of bupropion hydrochloride using RRLC/DAD and HPLC/MWD methods: stability study and application in pharmaceutical preparation and in synthetic mixtures with nicotine
El-Kosasy AM, et al.
Royal Society of Chemistry Advances, 5(79), 64274-64285 (2015)
Stability indicating HPLC and spectrophotometric methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates and related impurity
Abbas SS, et al.
Bulletin of Faculty of Pharmacy, Cairo University , 50(1), 49-59 (2012)
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