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PHR1720

氯米帕明

Name: 氯米帕明
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

氯米帕明盐酸盐

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About This Item

经验公式（希尔记法）:

C₁₉H₂₃ClN₂ · HCl

CAS号:

17321-77-6

分子量:

351.31

EC 号:

241-344-3

MDL编号:

MFCD00069234

UNSPSC代码:

41116107

PubChem化学物质编号:

329823573

NACRES:

NA.24

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C2360000

氯米帕明盐酸盐

Sigma-Aldrich

C7291

氯米帕明盐酸盐

Supelco

PHR1061

丙戊酸

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PHR1258

磷酸氯喹

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PHR1392

拉莫三嗪

USP

1140247

氯米帕明盐酸盐

Supelco

PHR1132

盐酸甲氧氯普胺

Sigma-Aldrich

H8885

羟嗪二盐酸盐

Supelco

PHR1340

吡拉明马来酸

Supelco

PHR1635

奥卡西平

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP
traceable to Ph. Eur. C2360000
traceable to USP 1140427

API类

clomipramine

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

Cl.CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13

InChI

1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H

InChI key

WIMWMKZEIBHDTH-UHFFFAOYSA-N

基因信息

human ... SLC6A4(6532)

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Clomipramine hydrochloride is one of the dibenzazepine tricyclic antidepressants that inhibits noradrenalin and serotonin reuptake in central nervous system. It also shows antimuscarinic properties.

应用

Clomipramine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in traditional Chinese medicine and pharmaceutical formulations by analytical and cyclodextrin-modified capillary zone electrophoresis techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3902 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

1140292

1140269

1140270

BP980

氯米帕明盐酸盐, British Pharmacopoeia (BP) Reference Standard

BP982

Clomipramine impurity D, British Pharmacopoeia (BP) Reference Standard

BP983

氯丙咪嗪杂质F, British Pharmacopoeia (BP) Reference Standard

象形图

GHS08,GHS07,GHS09

警示用语：

Danger

危险声明

H302,H336,H370,H410

预防措施声明

P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1 - STOT SE 3

靶器官

Central nervous system, Central nervous system,Cardiovascular

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Multicommutated flow system for the chemiluminometric determination of clomipramine in pharmaceutical preparations.

Marques KL, et al.

Analytica Chimica Acta, 518(1-2), 31-36 (2004)

Method for simultaneous determination of eight cyclic antidepressants by cyclodextrin-modified capillary zone electrophoresis: applications in pharmaceuticals.

Kou HS, et al.

Analytica Chimica Acta, 525(1), 23-30 (2004)

HPLC and GC?MS screening of Chinese proprietary medicine for undeclared therapeutic substances.

Liu SY, et al.

Journal of Pharmaceutical and Biomedical Analysis, 24(5-6), 983-992 (2001)

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主要文件

氯米帕明

Pharmaceutical Secondary Standard; Certified Reference Material

About This Item

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属性

等级

质量水平

Agency

API类

CofA

包装

技术

应用

包装形式

储存温度

SMILES字符串

InChI

InChI key

基因信息

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说明

一般描述

应用

分析说明

其他说明

附注

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警示用语：

危险声明

预防措施声明

危险分类

靶器官

储存分类代码

WGK

闪点(°F)

闪点(°C)

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分析证书(COA)

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