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安全信息

PHR1701

Supelco

醋酸曲安奈德

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

醋酸曲安奈德, 9α-氟-11β,16α,17α,21-四羟基-1,4-孕甾二烯-3,20-二酮-16,17-丙酮化合物, 9α-氟-16α-羟基波尼松龙 16α,17α-丙酮化合物

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About This Item

经验公式（希尔记法）:
C24H31FO6
CAS号:
76-25-5
分子量:
434.50
EC 号:
200-948-7
MDL编号:
MFCD00056834
UNSPSC代码:
41116107
PubChem化学物质编号:
329823564
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. T1900000
traceable to USP 1677002

API类

triamcinolone

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

基因信息

human ... NR3C1(2908)

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一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Triamcinolone Acetonide is a glucocorticoid and a derivative of pregnane, used mainly in the treatment of rheumatic disease, allergic and dermatologic symptoms.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Triamcinolone Acetonide may be used as a pharmaceutical standard for the determination of the analyte in drug dosage forms by high performance liquid chromatography and spectrophotometry.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2813 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险声明

H302,H360

危险分类

Acute Tox. 4 Oral - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Triamcinolone acetonide.
Jeal W and Faulds D
Drugs, 53(2), 257-280 (1997)
Simultaneous determination of terbinafine HCL and triamcinolone acetonide by UV derivative spectrophotometry and spectrodensitometry.
El-Saharty YS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 28(3-4), 569-580 (2002)
Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC.
Matysova L, et al.
Analytical and Bioanalytical Chemistry, 376(4), 440-443 (2003)
Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC.
Sudsakorn S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(5), 1273-1280 (2006)

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