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PHR1691

4-差向脱水四环素盐酸盐

Name: 4-差向脱水四环素 盐酸盐
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(4R,4aS,12aS)-4-(二甲氨基)-1,4,4a,5,12,12a-六氢-3,10,11,12a-四羟基-6-甲基-1,12-二氧代-2-并四苯甲酰胺单盐酸盐

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About This Item

经验公式（希尔记法）:

C₂₂H₂₂N₂O₇ · HCl

CAS号:

4465-65-0

分子量:

462.88

Beilstein:

3840711

MDL编号:

MFCD00151455

UNSPSC代码:

41116107

PubChem化学物质编号:

329823559

NACRES:

NA.24

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Supelco

PHR3175

脱水四环素盐酸盐

E0400000

4-差向脱水四环素盐酸盐

Supelco

94664

脱水四环素盐酸盐

Supelco

37921

4-差向脱水四环素盐酸盐

USP

1035708

脱水四环素盐酸盐

USP

1236506

4-差向脱水四环素盐酸盐

Supelco

PHR1041

四环素盐酸盐

Sigma-Aldrich

SAB5700220

Anti-HPRT1 antibody produced in rabbit

E0600000

4-差向四环素盐酸盐

Z743337

Cryo-Babies^® 标签

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. E0400000
traceable to USP 1236506

API类

chlortetracycline, tetracycline

CofA

current certificate can be downloaded

包装

pkg of 500 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H]2N(C)C

InChI

1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16+,22-;/m0./s1

InChI key

XBSQEFHDCDFNJU-MOMXNFOMSA-N

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一般描述

4-Epianhydrotetracycline hydrochloride is a degradation product of tetracyclines which are used as veterinary medicines.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

4-Epianhydrotetracycline hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in commercial bulk and pharmaceutical products by high performance liquid chromatography (HPLC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA6863 in the slot below. This is an example certificate only and may not be the lot that you receive.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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4-Epianhydrotetracycline

USP43-NF38: United States Pharmacopeia and National Formulary

United States Pharmacopeia/National Formulary, 6636-6636 (2013)

A high performance liquid chromatographic system for the analysis of tetracycline drug standards, analogs, degradation products and other impurities

Mack GD and Ashworth RB

Journal of Chromatographic Science, 16(3), 93-101 (1978)

Development and validation of an HPLC method for tetracycline-related USP monographs.

Emad M Hussien

Biomedical chromatography : BMC, 28(9), 1278-1283 (2014-03-13)

A novel reversed-phase HPLC method was developed and validated for the assay of tetracycline hydrochloride and the limit of 4-epianhydrotetracycline hydrochloride impurity in tetracycline hydrochloride commercial bulk and pharmaceutical products. The method employed L1 (3 µm, 150 × 4.6 mm) columns, a mobile phase

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4-差向脱水四环素 盐酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

About This Item

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API类

CofA

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SMILES字符串

InChI

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说明

一般描述

应用

分析说明

其他说明

附注

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储存分类代码

WGK

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4-差向脱水四环素盐酸盐