PHR1665
氯苯
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
氯苯
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关于此项目
经验公式（希尔记法）:
C6H5Cl
化学文摘社编号:
分子量:
112.56
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-628-5
Beilstein/REAXYS Number:
605632
MDL number:
产品名称
氯苯, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
MVPPADPHJFYWMZ-UHFFFAOYSA-N
InChI
1S/C6H5Cl/c7-6-4-2-1-3-5-6/h1-5H
SMILES string
Clc1ccccc1
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1601361
vapor density
3.86 (vs air)
vapor pressure
11.8 mmHg ( 25 °C)
CofA
current certificate can be downloaded
autoignition temp.
1178 °F
expl. lim.
7.1 %
packaging
ampule of 3x1.2 mL
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.524 (lit.)
bp
132 °C (lit.)
mp
−45 °C (lit.)
density
1.106 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Chlorobenzene may be used as a reference organic solvent standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Chlorobenzenes find use in domestic as well as industrial applications such as solvents, degreasers, pesticides and chemical intermediates for the synthesis of various chemical compounds. They are regarded as environmental pollutants because of their hazardous nature.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC1691 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Flam. Liq. 3 - Skin Irrit. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
80.6 °F
flash_point_c
27 °C
法规信息
危险化学品
此项目有
Optimization of temperature-controlled ionic liquid dispersive liquid phase microextraction combined with high performance liquid chromatography for analysis of chlorobenzenes in water samples
Kamarei F, et al.
Talanta, 83(1), 36-41 (2010)
Establishment of a knowledge base for prescreening residual solvents in pharmaceuticals
Qin L, et al.
Chromatographia, 59(7-8), 475-480 (2004)
Determination of residual solvent levels in bulk pharmaceuticals by capillary gas chromatography
Smith ID and Waters DG
Analyst, 116(12), 1327-1331 (1991)
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