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Merck
CN

PHR1660

Supelco

吲达帕胺

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

吲达帕胺, N-(2-甲基-2,3-二氢-1H-吲哚基)-3-氨磺酰基-4-氯-苯甲酰胺

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About This Item

经验公式(希尔记法):
C16H16ClN3O3S
CAS号:
分子量:
365.83
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to BP 999
traceable to Ph. Eur. I0150000
traceable to USP 1338801

API类

indapamide

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(N)(=O)=O

InChI

1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)

InChI key

NDDAHWYSQHTHNT-UHFFFAOYSA-N

基因信息

human ... SLC12A3(6559)

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Indapamide is a diuretic that is categorized under the family of benzothiadiazines compounds. It is an oral drug that is usually prescribed as an antihypertensive agent for patients with mild to moderate hypertension.

应用

Indapamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques and spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

象形图

Health hazard

警示用语:

Warning

危险声明

危险分类

Lact. - Repr. 2

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Quantitative determination of indapamide in pharmaceuticals and urine by high-performance liquid chromatography with amperometric detection.
Legorburu MJ, et al.
Journal of Chromatographic Science, 37(8), 283-287 (1999)
Development of new spectrophotometric methods for the determination of Indapamide in bulk and Pharmaceutical formulations.
Pai JB, et al.
International Journal of ChemTech Research, 3(2), 755-760 (2011)
Determination of certain drugs in binary mixtures formulations by second derivative ratio spectrophotometry and LC.
El-Gindy A, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 59(9), 703-712 (2004)
Comparison of spectrophotometric and an LC method for the determination perindopril and indapamide in pharmaceutical formulations.
Erk N
Journal of Pharmaceutical and Biomedical Analysis, 26(1), 43-52 (2001)

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