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PHR1657

Supelco

林可霉素 盐酸盐 一水合物

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Lincomycin hydrochloride monohydrate

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About This Item

经验公式（希尔记法）:
C18H34N2O6S · HCl · H2O
CAS号:
7179-49-9
分子量:
461.01
EC 号:
212-726-7
MDL编号:
MFCD00167245
UNSPSC代码:
41116107
PubChem化学物质编号:
329823535
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 215
traceable to Ph. Eur. L0650000
traceable to USP 1367005

API类

lincomycin

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

-10 to -25°C

SMILES字符串

Cl[H].[H]O[H].CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O

InChI

1S/C18H34N2O6S.ClH.H2O/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H;1H2/t9-,10-,11+,12-,13+,14-,15-,16-,18-;;/m1../s1

InChI key

LFZGYTBWUHCAKF-DCNJEFSFSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Lincomycin Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC0278 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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Liquid chromatographic method for separation of lincomycin from its related substances.
Orwa JA, et al.
Journal of Chromatography A, 829(1-2), 161-166 (1998)
Development and validation of a gradient HPLC method for the determination of clindamycin and related compounds in a novel tablet formulation.
Platzer DJ, White BA.
Journal of Pharmaceutical and Biomedical Analysis, 41(1), 84-88 (2006)
K Vučićević-Prčetić et al.
Journal of pharmaceutical and biomedical analysis, 56(4), 736-742 (2011-08-16)
Liquid chromatography with tandem mass spectrometry (LC/MS/MS) methods for the determination of gentamicin, lincomycin and spectinomycin in the presence of their impurities were developed and tested. Chromatographic separations were achieved using gradient elution on a C18 column. All components were

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