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PHR1638

盐酸阿夫唑嗪盐酸盐

Name: 盐酸阿夫唑嗪 盐酸盐
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, Uroxatral hydrochloride

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About This Item

经验公式（希尔记法）:

C₁₉H₂₇N₅O₄ · HCl

CAS号:

81403-68-1

分子量:

425.91

MDL编号:

MFCD00879135

UNSPSC代码:

41116107

PubChem化学物质编号:

329823527

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. A0325800
traceable to USP 1012917

API类

alfuzosin

CofA

current certificate can be downloaded

包装

ampule of 1 × 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3

InChI

1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H

InChI key

YTNKWDJILNVLGX-UHFFFAOYSA-N

基因信息

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Alfuzosin hydrochloride may be used as a pharmaceutical reference standard for the quantification of alfuzosin hydrochloride levels in pharmaceutical formulations by reverse phase high-performance liquid chromatography (RP-HPLC), high performance thin layer chromatography (HPTLC) and spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

Alfuzosin hydrochloride is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.

附注

To see an example of a Certificate of Analysis for this material enter LRAA5304 in the slot below. This is an example certificate only and may not be the lot that you receive.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number

LRAD3355

LRAC2711

LRAA5304

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Development and validation of reverse phase high performance liquid chromatography and high performance thin layer chromatography methods for estimation of alfuzosin hydrochloride in bulk and in pharmaceutical formulations

Patel DB and Patel NJ

International Journal of ChemTech Research, 1(4), 985-990 (2009)

Validated HPLC and HPTLC stability-indicating methods for determination of alfuzosin hydrochloride in bulk powder and pharmaceutical formulations

Salah FA, et al.

Journal of Separation Science, 29(18), 2716-2724 (2006)

Spectrophotometric determination of alfuzosin HCl in pharmaceutical formulations with some sulphonephthalein dyes

Ashour S, et al.

International Journal of Biomedical Science : IJBS, 2(3), 273-278 (2006)

Development of new spectrophotometric methods for the determination of Alfuzosin hydrochloride in bulk and pharmaceutical formulations

Kumar DR, et al.

Orient. J. Chem., 24(2), 725-728 (2008)

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盐酸阿夫唑嗪 盐酸盐