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PHR1619

Supelco

二丙酸倍氯米松

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

二丙酸倍氯米松, 9-氯-11β,17,21-三羟基-16β-甲基孕甾-1,4-二烯-3,20-二酮-17,21-二丙酸酯

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About This Item

经验公式（希尔记法）:
C28H37ClO7
CAS号:
5534-09-8
分子量:
521.04
EC 号:
226-886-0
MDL编号:
MFCD00135613
UNSPSC代码:
41116107
PubChem化学物质编号:
329823513
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 30
traceable to Ph. Eur. B0305000
traceable to USP 1048506

API类

beclometasone

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C

InChI

1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1

InChI key

KUVIULQEHSCUHY-XYWKZLDCSA-N

基因信息

human ... NR3C1(2908)

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相关类别

一般描述

Beclomethasone Dipropionate is a second generation anti-inflammatory corticosteroid used for the treatment of allergic rhinitis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Beclomethasone Dipropionate may be used as a pharmaceutical secondary reference standard for the determination of the analyte in biological fluids and ear drops formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2965 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相关产品

产品编号
说明
价格

1048506

二丙酸倍氯米松, United States Pharmacopeia (USP) Reference Standard

B0305000

二丙酸倍氯米松, anhydrous, European Pharmacopoeia (EP) Reference Standard

Y0000352

二丙酸倍氯米松, European Pharmacopoeia (EP) Reference Standard

Y0000351

Beclometasone dipropionate monohydrate, European Pharmacopoeia (EP) Reference Standard

Y0000469

二丙酸倍氯米松, European Pharmacopoeia (EP) Reference Standard

Y0001073

丙酸倍氯米松杂质F, European Pharmacopoeia (EP) Reference Standard

BP030

二丙酸倍氯米松（氯地米松）, British Pharmacopoeia (BP) Assay Standard

1048517

Beclomethasone Dipropionate Related Compound A, United States Pharmacopeia (USP) Reference Standard

1048543

Beclomethasone Dipropionate Related Compound H, United States Pharmacopeia (USP) Reference Standard

象形图

Health hazard
GHS08

警示用语：

Warning

危险声明

H361fd,H373

危险分类

Repr. 2 - STOT RE 2

靶器官

Adrenal gland,Immune system,Bone

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of beclomethasone dipropionate, clotrimazole, chloramphenicol and lidocaine in pharmaceutical formulations using a novel RP-HPLC method
Reddy MU, et al.
International Journal of Pharma and Bio Sciences, 2(1), 453-462 (2011)
Efficacy and safety of beclomethasone dipropionate nasal aerosol in children with perennial allergic rhinitis
Berger WE, et al.
Annals of Allergy, Asthma & Immunology, 115(2), 130-136 (2015)
Simultaneous determination of beclomethasone, beclomethasone monopropionate and beclomethasone dipropionate in biological fluids using a particle beam interface for combining liquid chromatography with negative-ion chemical ionization mass spectrometry
Girault J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 564(1), 43-53 (1991)
Efficacy and safety of oral beclomethasone dipropionate in ulcerative colitis: a systematic review and meta-analysis
Manguso F, et al.
Testing, 11(11), e0166455-e0166455 (2016)
Determination of beclomethasone dipropionate, clotrimazole, chloramphenicol and lidocaine in pharmaceutical formulations using a novel RP-HPLC method
Reddy MU, et al.
International Journal of Pharmacy and Biological Sciences, 2(1), 453-462 (2011)

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