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经验公式(希尔记法):
C12H22O11
化学文摘社编号:
分子量:
342.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
225-027-7
Beilstein/REAXYS Number:
93773
MDL number:
产品名称
乳果糖, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
JCQLYHFGKNRPGE-WJONTELPSA-N
InChI
1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12+/m1/s1
SMILES string
OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. L0130000
traceable to USP 1356803
API family
lactulose
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Lactulose may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Lactulose is a disaccharide that finds immense applications in medicine, nutrition and dairy technology. It is utilized as a medicine in the treatment of portal systemic encephalopathy and chronic constipation.
Lactulose is a disaccharide that finds immense applications in medicine, nutrition and dairy technology. It is utilized as a medicine in the treatment of portal systemic encephalopathy and chronic constipation.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7605 in the slot below. This is an example certificate only and may not be the lot that you receive.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Chromatographic determination of lactulose
Martinez-Castro I, et al.
Chromatographia, 23(2), 132-136 (1987)
Use of an automated robotic system for the extraction and on-line high-performance liquid chromatographic analysis of pharmaceutical formulations
Van der Voorden EC, et al.
Chemometrics and Intelligent Laboratory Systems, 17(1), 129-135 (1992)
Kostan W Reisinger et al.
Journal of pediatric gastroenterology and nutrition, 59(6), 720-724 (2014-08-12)
The incidence of necrotizing enterocolitis (NEC) is higher in formula-fed babies than in breast-fed babies, which may be caused by breast-feeding-induced gut maturation. The effect of breast-feeding on gut maturation has been widely studied in animal models. This study aimed
J Zhao et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(6), 794-802 (2014-03-20)
Small intestinal bacterial overgrowth (SIBO) may be a cause of irritable bowel syndrome (IBS); however, current investigations have important limitations. We aimed to identify clinically relevant diagnostic criteria for SIBO based on lactulose hydrogen breath test (LHBT) alone and combined
A A Guerra-Ordaz et al.
Applied and environmental microbiology, 80(16), 4879-4886 (2014-06-08)
The potential of a prebiotic oligosaccharide lactulose, a probiotic strain of Lactobacillus plantarum, or their synbiotic combination to control postweaning colibacillosis in pigs was evaluated using an enterotoxigenic Escherichia coli (ETEC) K88 oral challenge. Seventy-two weanlings were fed four diets:
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