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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to BP 841
traceable to Ph. Eur. H1435000
traceable to USP 1333003
API类
hydroxyzine
CofA
current certificate can be downloaded
包装
pkg of 1 g
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI
1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI key
ANOMHKZSQFYSBR-UHFFFAOYSA-N
基因信息
human ... HRH1(3269)
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一般描述
Hydroxyzine dihydrochloride is an antihistaminic drug and a member of the diphenylmethanes family. It exerts its action by blocking the action of histamine, a substance in the body that causes allergic symptoms.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
Hydroxyzine dihydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by spectrophotometry and high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA4723 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
相关产品
产品编号
说明
价格
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Optimized and validated spectrophotometric methods for the determination of hydroxyzine hydrochloride in pharmaceuticals and urine using iodine and picric acid
Rajendraprasad N, et al
J. Serb. Chem. Soc., 76(11), 1551-1560 (2011)
Green approach towards the determination of hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms.
Mumtaz A, et al.
Pakistan Journal of Pharmaceutical Sciences, 27(5), 911-918 (2014)
A High performance liquid chromatography method for determination of hydroxyzine hydrochloride in syrup
Brand MA, et al.
Latin American Journal of Pharmacy, 30(9), 1798-1802 (2011)
Sensitive and selective extractive spectrophotometric method for the determination of hydroxyzine dihydrochloride in pharmaceuticals
Rajendraprasad N, et al.
Journal of the Mexican Chemical Society, 54(4), 233-239 (2010)
Diphenylmethane antihistaminics
Drugs and Poisons in Humans: A Handbook of Practical Analysis, 315-324 (2005)
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