SMILES string
[Na+].S([C@H](CCc5c(cccc5)C(O)(C)C)c2cc(ccc2)\C=C\c3nc4c(cc3)ccc(c4)Cl)CC1(CC1)CC(=O)[O-]
InChI
1S/C35H36ClNO3S.Na/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39);/q;+1/p-1/b15-10+;/t32-;/m1./s1
InChI key
LBFBRXGCXUHRJY-HKHDRNBDSA-M
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001434, traceable to USP 1446859
API family
montelukast
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
用于质量控制的药物二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。孟鲁司特钠是一种口服的白三烯受体拮抗药，可通过抑制半胱氨酰白三烯（CysLT1）受体而发挥作用。它可有效对抗引起支气管收缩和气道炎症导致哮喘问题的白三烯。
Application
孟鲁司特钠可用作药物参考标准品，用于通过色谱法和分光光度技术测定散装药物和药物制剂中的分析物。
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
Analysis Note
这些二级标准品可追溯至USP、EP和BP一级标准品。
Other Notes
如需查看该材料的检验报告示例，请在下方插槽中输入 LRAB3617。这只是一个示例证书，可能不是您收到的批次。
本有证标准物质 (CRM) 按照 ISO 17034 和 ISO/IEC 17025 生产和认证。有关本 CRM 使用的所有信息，请参见检验报告。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Montelukast Sodium
USP42-NF37
United States Pharmacopeia/National Formulary, 37(2), 2974-2974 (2018)
Spectrophotometric method for quantitative determination of montelukast in bulk, pharmaceutical formulations and human serum
Arayne MS, et al.
Journal of Analytical Chemistry, 64(7), 690-695 (2009)
HPTLC determination of montelukast sodium in bulk drug and in pharmaceutical preparations
Sane R, et al.
J. Planar Chromatogr., 17(1), 75-78 (2004)
Santa Mandal et al.
Inhalation toxicology, 32(7), 299-310 (2020-07-01)
To explore the therapeutic role of a single dose combination of montelukast (MON) and dexamethasone (DXM) through intra-peritoneal route against paraquat (PQ)-intoxicated experimental Wistar rats. In vivo the survival rate was investigated following the administration of both MON and DXM
Sheng-Hua Wu et al.
Pediatrics international : official journal of the Japan Pediatric Society, 56(3), 315-322 (2013-12-05)
Previous studies suggested that leukotrienes (LT) were involved in the pathogenesis of Henoch-Schönlein purpura (HSP). This study investigated the efficacy of an add-on therapy with montelukast in the treatment of HSP. In this four-center, double-blind, placebo-controlled, parallel paired comparative study
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持