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Merck
CN

PHR1598

Supelco

盐酸普拉克索

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Pramipexole dihydrochloride monohydrate, (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino) benzothiazole dihydrochloride

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About This Item

经验公式(希尔记法):
C10H17N3S · 2HCl · H2O
分子量:
302.26
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. Y0001266
traceable to USP 1553859

API类

pramipexole

CofA

current certificate can be downloaded

包装

pkg of 500 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

InChI

1S/C10H17N3S.2ClH.H2O/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;;/h7,12H,2-6H2,1H3,(H2,11,13);2*1H;1H2/t7-;;;/m0.../s1

InChI key

APVQOOKHDZVJEX-QTPLPEIMSA-N

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一般描述

Pramipexole Dihydrochloride is a non-ergot dopamine agonist widely used for the treatment of early and advanced Parkinson′s disease (PD). It is also used to treat restless legs syndrome.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Pramipexole Dihydrochloride may be used as a secondary pharma standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA4714 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - STOT SE 3

靶器官

Central nervous system

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Ecofriendly spectrophotometric method development and their validation for quantitative estimation of Pramipexole Dihyrochloride using mixed hydrotropic agent
Jain N, et al.
Journal of Chemical and Pharmaceutical Research , 3(1), 548-552 (2009)
Spectrophotometric methods for the estimation of pramipexole dihydrochloride in pharmaceutical formulations
Gurupadayya MB, et al.
World Journal of chemistry, 4(2), 157-160 (2009)

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