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Merck
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安全信息

PHR1595

Supelco

Polymyxin B Sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Polymyxin B sulfate

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About This Item

CAS号:
1405-20-5
EC 号:
215-774-7
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 1028
traceable to Ph. Eur. P2400000
traceable to USP 1547007

API类

polymyxin

CofA

current certificate can be downloaded

包装

pkg of 500 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

InChI

1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)

InChI key

HNDFYNOVSOOGDU-UHFFFAOYSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Polymyxin B Sulfate is used for the treatment of gram-negative bacterial infections caused particularly by Pseudomonas aeruginosa and Escherichia coli.

应用

Polymyxin B Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography and capillary electrophoresis, respectively.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC0300 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
LRAD4397
LRAC0365
LRAD0395
LRAC0300
LRAA4711

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Sensitive detection of polymyxin B sulfate at the nanogram level using enhanced resonance scattering signals and decreased fluorescence signals with thioglycolic acid capped CdTe/CdS quantum dots as probe.
Shen Y, et al.
Sensors and Actuators B, Chemical, 188, 555-563 (2013)
Development of a liquid chromatographic method for ear drops containing neomycin sulphate, polymyxin B sulphate and dexamethasone sodium phosphate.
Pendela M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 751-757 (2004)
Simultaneous determination of neomycin sulfate and polymyxin B sulfate by capillary electrophoresis with indirect UV detection.
Srisom P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1013-1018 (2007)

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