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安全信息

PHR1572

Supelco

盐酸羟甲唑啉

certified reference material, pharmaceutical secondary standard

别名:

羟甲唑啉 盐酸盐, 2-（3-羟基-2,6-二甲基-4-叔丁基苄基）-2-咪唑啉 盐酸盐

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About This Item

经验公式（希尔记法）:
C16H24N2O · HCl
CAS号:
2315-02-8
分子量:
296.84
EC 号:
219-015-0
MDL编号:
MFCD00058147
UNSPSC代码:
41116107
PubChem化学物质编号:
329823480
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. O0290000
traceable to USP 1486004

API类

oxymetazoline

CofA

current certificate can be downloaded

包装

pkg of 10 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C

InChI

1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H

InChI key

BEEDODBODQVSIM-UHFFFAOYSA-N

基因信息

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

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一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxymetazoline hydrochloride belongs to the category of non-selective adrenergic drugs commonly used as eye and nose drops.

应用

Oxymetazoline hydrochloride may be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

盐酸羟甲唑啉是一种部分 α2A-肾上腺素受体激动剂；5-HT1A、5-HT1B 和 5-HT1D 血清素受体的激动剂。它是 5-HT1C 血清素受体的混合激动剂-拮抗剂。

附注

To see an example of a Certificate of Analysis for this material enter LRAB5024 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相关产品

产品编号
说明
价格

Y0001044

羟甲唑啉杂质A, European Pharmacopoeia (EP) Reference Standard

O0290000

羟甲唑啉 盐酸盐, European Pharmacopoeia (EP) Reference Standard

1486015

Oxymetazoline Related Compound A, United States Pharmacopeia (USP) Reference Standard

43329

2-(4-tert-Butyl-3-hydroxy-2,6-dimethylphenyl)acetamide, reference material

PHR2215

Oxymetazoline Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR9134

2-(4-tert-Butyl-3-hydroxy-2,6-dimethylphenyl)acetic acid, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9161

2-(4-叔丁基-3-羟基-2,6-二甲基苯基)乙腈, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

象形图

Skull and crossbonesCorrosion
GHS06,GHS05

警示用语：

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1

储存分类代码

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Spectrophotometric determination of oxymetazoline hydrochloride based on the oxidation reactions
Al-Sabha NT and Rasheed AB
Jordan Journal of Chemistry, 146(605), 1-9 (2011)

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