PHR1519
磺胺醋酰钠
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
Sulfacetamide sodium salt monohydrate
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经验公式（希尔记法）:
C8H9N2NaO3S · H2O
化学文摘社编号:
分子量:
254.24
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
磺胺醋酰钠, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
IHCDKJZZFOUARO-UHFFFAOYSA-M
SMILES string
NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O
InChI
1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. S1700000
traceable to USP 1624006
API family
sulfacetamide
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Sulfacetamide Sodium may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by spectrometric technique and micellar electro-kinetic chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Sulfacetamide Sodium belongs to the class of sulfonamides, widely used in ophthalmic preparations, to treat different ocular infections such as corneal ulcers and conjunctivitis. It shows bactericidal activity against susceptible microorganisms.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3326 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Validation of a stability-indicating spectrometric method for the determination of sulfacetamide sodium in pure form and ophthalmic preparations
Ahmed S, et al.
Journal of Pharmacy & Bioallied Sciences, 9(2), 126-126 (2017)
Pharmacology, 9(2), 126-126 (2014)
Determination of prednisolone acetate, sulfacetamide and phenylefrine in local pharmaceutical preparations by micellar electrokinetic chromatography
Gallego LMJ and Arroyo PJ
Journal of Pharmaceutical and Biomedical Analysis, 31(5), 873-884 (2003)
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