PHR1513
恩诺沙星
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
恩诺沙星
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关于此项目
经验公式（希尔记法）:
C19H22FN3O3
化学文摘社编号:
分子量:
359.39
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5307824
产品名称
恩诺沙星, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
SMILES string
CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4
InChI key
SPFYMRJSYKOXGV-UHFFFAOYSA-N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001259
traceable to USP 1235900
API family
enrofloxacin
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Enrofloxacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and water samples by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Enrofloxacin is classified under the second generation quinolone antibiotics, known as ′fluoroquinolones′. It is a component of several medicines used to treat urinary tract infections, infections of the gastrointestinal tract, respiratory tract infections, infections of the skin structure as well as surgical prophylaxis.
Enrofloxacin is classified under the second generation quinolone antibiotics, known as ′fluoroquinolones′. It is a component of several medicines used to treat urinary tract infections, infections of the gastrointestinal tract, respiratory tract infections, infections of the skin structure as well as surgical prophylaxis.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0027 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Withdrawal time of four pharmaceutical formulations of enrofloxacin in poultry according to different maximum residues limits.
Martin SB, et al.
Journal of Veterinary Pharmacology and Therapeutics, 33(3), 246-251 (2010)
Enrofloxacin assay validation and pharmacokinetics following a single oral dose in chickens.
Da Silva RG, et al.
Journal of Veterinary Pharmacology and Therapeutics, 29(5), 365-372 (2006)
Multi-class determination of around 50 pharmaceuticals, including 26 antibiotics, in environmental and wastewater samples by ultra-high performance liquid chromatography?tandem mass spectrometry.
Gracia-Lor E, et al.
Journal of Chromatography A, 1218(16), 2264-2275 (2011)
Validation of a novel HPLC sorbent material for the determination of ten quinolones in human and veterinary pharmaceutical formulations.
Samanidou VF, et al.
Journal of Separation Science, 28(18), 2444-2453 (2005)
Jochen Springer et al.
Stroke, 45(12), 3675-3683 (2014-10-30)
Muscle wasting is a common complication accompanying stroke. Although it is known to impair poststroke recovery, the mechanisms of subacute catabolism after stroke have not been investigated in detail. The aim of this study is to investigate mechanisms of local
商品
LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.
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