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Merck
CN

PHR1500

Supelco

咪唑烷基脲

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
咪唑烷基脲, N,N′′-亚甲基双[N′-[3-(羟甲基)-2,5-二氧基-4-咪唑烷]-尿素
经验公式(希尔记法):
C11H16N8O8
CAS号:
分子量:
388.29
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to USP 1336806

API类

imidurea

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

OCN1C(NC(=O)NCNC(=O)NC2N(CO)C(=O)NC2=O)C(=O)NC1=O

InChI

1S/C11H16N8O8/c20-2-18-4(6(22)16-10(18)26)14-8(24)12-1-13-9(25)15-5-7(23)17-11(27)19(5)3-21/h4-5,20-21H,1-3H2,(H2,12,14,24)(H2,13,15,25)(H,16,22,26)(H,17,23,27)

InChI key

ZCTXEAQXZGPWFG-UHFFFAOYSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

用于:
研究药物营养敏感筛选的药理学研究,即从线粒体呼吸到糖酵解的迁移能量代谢
涉及纳米结构植物载体局部活性分子递送的治疗研究
用作抗氧化剂的局部制剂
Imidurea may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA3048 in the slot below. This is an example certificate only and may not be the lot that you receive.

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象形图

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警示用语:

Warning

危险声明

预防措施声明

危险分类

Skin Sens. 1B

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Analysis of preservative in pharmaceutical products
Fahelelbom KMS, et al.
Pharmaceutical Reviews, 5(1), 3960-3968 (2007)
Validation of a micellar electrokinetic capillary chromatography method for the determination of imidurea, methyl and propylparabens in a pharmaceutical ointment
Baalbaki B, et al.
Analytica Chimica Acta, 463(1), 15-20 (2002)
María Castro-Puyana et al.
Electrophoresis, 26(20), 3960-3968 (2005-10-12)
EKC using a neutral CD as chiral selector was applied in this work to the development of a method enabling the enantiomeric separation of ketoconazole and terconazole antifungals. The influence of different experimental conditions such as temperature, CD concentration, pH

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