Spectinomycin

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Spectinomycin Hydrochloride is an aminocyclitol antibiotic, widely used in human medicine for the treatment of uncomplicated gonorrhea and also in veterinary medicine to treat bacterial respiratory and enteric infections. Its mode of action involves the inhibition of protein synthesis in the bacterial cell wall.

Spectinomycin Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography with evaporative light scattering detection (HPLC−ELSD).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

作用方式：通过干扰肽基 tRNA 的转位抑制蛋白质合成（延伸）。
抗菌谱：革兰氏阴性和革兰氏阳性菌（仅包括淋球菌）。
抗性机理：rpsE（核糖体蛋白 S5 的基因）的突变可阻止壮观霉素的结合。

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC1683 in the slot below. This is an example certificate only and may not be the lot that you receive.