PHR1423
硝普钠
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
硝普钠 二水合物, SNP, 五氰基亚硝酰基铁酸钠, 硝基铁酸氰化钠, 硝普盐 钠
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关于此项目
线性分子式:
Na2[Fe(CN)5NO] · 2H2O
化学文摘社编号:
分子量:
297.95
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
238-373-9
MDL number:
产品名称
硝普钠, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
OIRZWVYIQXBRFC-UHFFFAOYSA-N
InChI
1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;
SMILES string
[Na+].[Na+].[H]O[H].[H]O[H].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1614501
API family
sodium nitroprusside
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
这些二级标准为USP、EP和BP 主要标准提供了多种可追溯性。
Application
硝普钠可以作为分光光度法的试剂，用于使用分光光度法分析药物制剂中的美洛昔康。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
General description
用于 质量控制的认证药物二级标准品为 制药实验室和制造商提供了一种方便且具有成本效益 的主要标准替代品硝普钠已被广泛用作控制高血压的药物，它可通过作用于小动脉平滑肌来抑制血压升高。
Other Notes
要查看此材料的分析证书示例，请在下面的空格中输入 LRAB7818。这只是一个示例证书，可能不是您收到的批次。
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Rohit Ramchandra et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(3), R271-R280 (2014-05-23)
Heart failure (HF) is associated with increased cardiac and renal sympathetic drive, which are both independent predictors of poor prognosis. A candidate mechanism for the centrally mediated sympathoexcitation in HF is reduced synthesis of the inhibitory neuromodulator nitric oxide (NO)
Gary J Hodges et al.
Experimental physiology, 99(2), 381-392 (2013-11-12)
What is the central question of this study? Previous work has produced the counterintuitive finding that the vasoconstrictor neurotransmitters noradrenaline and neuropeptide Y are involved in vasodilatation. We aimed to discover whether sympathetic neurotransmitters are required for the sustained vasodilatation
Spectrophotometric determination of meloxicam by sodium nitroprusside and 1, 10-phenanthroline reagents in bulk and its pharmaceutical formulation
Gurupadayya MB, et al.
Indian Journal of Chemical Technology, 20, 111-115 (2013)
Laura A E Cox et al.
Shock (Augusta, Ga.), 43(4), 322-326 (2015-01-08)
Although endothelial dysfunction is central to the pathogenesis of sepsis, no specific and clinically applicable marker for endothelial dysfunction is currently available. Endocan, a proteoglycan excreted by endothelial cells in response to inflammatory cytokines, may serve as such a marker.
Antihypertensive Drugs (1997)
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