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PHR1393

三水合氨苄青霉素

Name: 三水合氨苄青霉素
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

氨苄西林三水合物, 氨苄青霉素

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About This Item

经验公式（希尔记法）:

C₁₆H₁₉N₃O₄S · 3H₂O

CAS号:

7177-48-2

分子量:

403.45

Beilstein:

5399534

EC 号:

200-709-7

MDL编号:

MFCD00072036

UNSPSC代码:

41116107

PubChem化学物质编号:

329823367

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 785
traceable to Ph. Eur. A1000000
traceable to USP 1033000/1033407

API类

ampicillin

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

198-200 °C (dec.) (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChI key

RXDALBZNGVATNY-CWLIKTDRSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Ampicillin trihydrate may be used as an analytical reference standard for the determination of ampicillin in plasma samples and pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

一种具有连接到青霉素结构上的氨基侧链的 β-内酰胺抗生素。通过灭活细菌细胞膜内表面的转肽酶而抑制细菌细胞壁合成（肽聚糖交联）的青霉素衍生物。仅对生长中的大肠埃希菌具有杀菌作用。耐药方式：氨苄西林的 β-内酰胺环被 β-内酰胺酶裂解。抗菌谱：革兰阴性菌和革兰阳性菌。

附注

To see an example of a Certificate of Analysis for this material enter LRAA1900 in the slot below. This is an example certificate only and may not be the lot that you receive.

警示用语：

Danger

危险声明

H315,H317,H319,H334,H335

预防措施声明

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

危险分类

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

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Determination of ampicillin in human plasma by high-performance liquid chromatography using ultraviolet detection.

Akhtar MJ, et al.

Journal of Pharmaceutical and Biomedical Analysis, 11(4-5), 375-378 (1993)

Determination of amoxicillin, ampicillin, and penicillin G using a flow injection analysis method with chemiluminescence detection.

Chivulescu AI, et al.

Rev. Roum. Chim., 56(3), 247-254 (2011)

Antibiotic resistance is widespread in urban aquatic environments of Rio de Janeiro, Brazil.

Felipe H Coutinho et al.

Microbial ecology, 68(3), 441-452 (2014-05-14)

Bacterial resistance to antibiotics has become a public health issue. Over the years, pathogenic organisms with resistance traits have been studied due to the threat they pose to human well-being. However, several studies raised awareness to the often disregarded importance

Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice.

Hazem E Ghoneim et al.

The Journal of infectious diseases, 209(9), 1459-1468 (2013-11-26)

Secondary bacterial pneumonia is a significant cause of morbidity and mortality during influenza, despite routine use of standard antibiotics. Antibiotic-induced immunopathology associated with bacterial cell wall lysis has been suggested to contribute to these poor outcomes. Using Streptococcus pneumoniae in

Anaerobiospirillum succiniciproducens-induced bacteremia in a healthy man.

Ryota Inokuchi et al.

The American journal of emergency medicine, 32(7), 812-812 (2014-01-21)

Anaerobiospirillum succiniciproducens is rarely associated with bacteremia but results in significant mortality. Almost all reported bacteremia cases have occurred in immunocompromised hosts, such as those with alcoholic liver disease, atherosclerosis, recent surgery, malignancies, or acquired immunodeficiency syndrome. We describe here

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三水合氨苄青霉素

Pharmaceutical Secondary Standard; Certified Reference Material

About This Item

属性

等级

质量水平

Agency

API类

CofA

技术

mp

应用

格式

储存温度

SMILES字符串

InChI

InChI key

相关类别

说明

一般描述

应用

生化/生理作用

附注

相关产品

相关产品

安全信息

象形图

警示用语：

危险声明

预防措施声明

危险分类

靶器官

WGK

闪点(°F)

闪点(°C)

法规信息

文件

分析证书(COA)

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