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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

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PHR1380

Supelco

伊维菌素

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

伊维菌素, 22,23-二氢阿维菌素 B1, MK-933

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500 MG
CN¥7,012.18
1 G
CN¥10,399.40

CN¥7,012.18

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500 MG
CN¥7,012.18
1 G
CN¥10,399.40

About This Item

CAS号:
70288-86-7
EC 号:
274-536-0
MDL编号:
MFCD00869511
UNSPSC代码:
41116107
PubChem化学物质编号:
329823357
NACRES:
NA.24

CN¥7,012.18

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 864
traceable to Ph. Eur. I8000010
traceable to USP 1354309

API类

ivermectin

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[H][C@@]1(O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C6/CO[C@]7([H])[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]67O)O2)[C@@H](C)CC

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此商品
M5310M3516M1180
Mineral oil BioUltra, Molecular Biology

69794

Mineral oil

Mineral oil light oil, suitable for mouse embryo cell culture, BioXtra

M5310

Mineral oil

Mineral oil suitable for preparation of Nujol mulls for infrared spectroscopy, light oil

M3516

Mineral oil

Mineral oil meets USP testing specifications

M1180

Mineral oil

technique(s)

PCR: suitable

technique(s)

cell culture | embryo: suitable

technique(s)

PCR: suitable

technique(s)

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

grade

for molecular biology

grade

-

grade

-

grade

-

form

viscous liquid

form

light oil

form

light oil

form

liquid

cation traces

Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤50 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Zn: ≤5 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Na: ≤50 mg/kg, Cr: ≤5 mg/kg, Pb: ≤5 mg/kg, Mg: ≤5 mg/kg

cation traces

-

cation traces

-

cation traces

-

UV absorption

λ: 260 nm Amax: 0.7, λ: 280 nm Amax: 1.0

UV absorption

-

UV absorption

-

UV absorption

-

一般描述

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
依维菌素是阿维菌素B1的衍生物，用于杀灭兽医应用中的内部和外部寄生物。它还被用作控制旋盘尾丝虫的潜在药物，这种寄生虫经鉴定是人类′河盲症′的病因。[1]

应用

依维菌素可用作药物参考标准品，用于通过色谱技术测定药物制剂和血浆样品中的分析物。[2][3]
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可追溯至USP、EP和BP一级标准品。

其他说明

该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

要查看该材料的分析证书示例，请在下面的栏位中输入 LRAA1636。这只是一个示例证书，可能不是您收到的批次。

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险声明

H300,H311,H410

危险分类

Acute Tox. 1 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Feng Xiong et al.
    The Plant cell, 32(12), 3812-3824 (2020-09-30)
    Plant roots are sustained through meristem activity at the root tip. Two transcriptional pathways, one mediated by PLETHORAs (PLTs) and the other by SHORTROOT and SCARECROW, play major roles in root meristem development. The role of PLTs during root meristem
    Liquid chromatographic determination of ivermectin in animal plasma with trifluoroacetic anhydride and N-methylimidazole as the derivatization reagent
    de Montigny P, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 8(6), 507-511 (1990)
    Ivermectin (3.15%) long-acting formulations in cattle: absorption pattern and pharmacokinetic considerations
    Lifschitz A, et al.
    Veterinary Parasitology, 147(3-4), 303-310 (2007)
    Ivermectin disposition kinetics after subcutaneous and intramuscular administration of an oil-based formulation to cattle
    Lifschitz A, et al.
    Veterinary Parasitology, 86(3), 203-215 (1999)

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