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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to Ph. Eur. S1800000
traceable to USP 1625009
API类
sulfadiazine
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
253 °C (dec.) (lit.)
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-30°C
SMILES字符串
Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2
InChI
1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)
InChI key
SEEPANYCNGTZFQ-UHFFFAOYSA-N
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一般描述
Sulfadiazine is a bacteriostatic drug, that belongs to the class of medication referred as sulfonamide antibiotics. It is generally used in the treatment of cerebral meningitis, pneumonia, staphylococcal and streptococcal sepsis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
Sulfadiazine may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAC3953 in the slot below. This is an example certificate only and may not be the lot that you receive.
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危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2
WGK
WGK 2
Development and validation of a stability-indicating HPLC method for the simultaneous determination of sulfadiazine sodium and trimethoprim in injectable solution formulation
Ghanem MM and Abu-Lafi SA
Scientia Pharmaceutica, 81(1), 167-182 (2013)
Determination of the content and the related substances of silver sulfadiazine gel by HPLC
Li Y, et al.
Chinese Journal of Hospital Pharmacy, 24(8), 474-474 (2004)
33 - Antimicrobial Drugs
Synthesis of Essential Drugs, 499-523 (2006)
Sulfonamide antibiotics
Connor EE
Primary Care Update for OB/GYNS, 5(1), 32-35 (1998)
Sulfadiazine
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 4106-4106 (2018)
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