PHR1334
叶酸杂质A
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
N-（4-氨基苯甲酰基）-L-谷氨酸
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经验公式（希尔记法）:
C12H14N2O5
化学文摘社编号:
分子量:
266.25
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
224-261-7
Beilstein/REAXYS Number:
2816320
MDL number:
产品名称
叶酸杂质A, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1
InChI key
GADGMZDHLQLZRI-VIFPVBQESA-N
SMILES string
Nc1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001242
traceable to USP 1019870
API family
folic acid
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3324 in the slot below. This is an example certificate only and may not be the lot that you receive.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Joachim Michael Matz et al.
Cell reports, 26(2), 356-363 (2019-01-10)
Folate metabolism is essential for DNA synthesis and a validated drug target in fast-growing cell populations, including tumors and malaria parasites. Genome data suggest that Plasmodium has retained its capacity to generate folates de novo. However, the metabolic plasticity of
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