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Merck
CN

PHR1281

Supelco

阿苯达唑

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
5-(丙硫基)-2-苯并咪唑氨基甲酸甲酯
经验公式(希尔记法):
C12H15N3O2S
CAS号:
分子量:
265.33
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to BP 763
traceable to Ph. Eur. A0325100
traceable to USP 1012553

API类

albendazole

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Albendazole (ABZ) is an anthelminthic drug, used in both human and veterinary medication. it is widely used to eliminated the effects of lymphatic filariasis.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA0016 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Health hazardEnvironment

警示用语:

Warning

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

靶器官

Adrenal gland,Blood,male reproductive organs,spleen

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

农药列管产品

分析证书(COA)

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Peiling Yap et al.
The American journal of tropical medicine and hygiene, 89(1), 23-31 (2013-05-22)
Post-treatment soil-transmitted helminth re-infection patterns were studied as part of a randomized controlled trial among school-aged children from an ethnic minority group in Yunnan province, People's Republic of China. Children with a soil-transmitted helminth infection (N = 194) were randomly
Aprilianto E Wiria et al.
PloS one, 8(3), e57899-e57899 (2013-03-26)
Helminth infections are proposed to have immunomodulatory activities affecting health outcomes either detrimentally or beneficially. We evaluated the effects of albendazole treatment, every three months for 21 months, on STH, malarial parasitemia and allergy. A household-based cluster-randomized, double-blind, placebo-controlled trial
Ruth Ann Baird et al.
Neurology, 80(15), 1424-1429 (2013-04-10)
To review the evidence base for different treatment strategies in intraparenchymal neurocysticercosis in adults and children. A literature search of Medline, EMBASE, LILACS, and the Cochrane Database from 1980 to 2008, updated in 2012, resulted in the identification of 10
Ahmed M Abdel-tawab et al.
British journal of clinical pharmacology, 68(5), 737-742 (2009-11-18)
Albendazole (ABZ) is used in several anthelminthic drug programs. ABZ side-effects are generally mild, but ABZ-induced pancytopenia may be serious. In filariasis programmes, it may be necessary to administer ABZ to breastfeeding women. Few data are available on safety of
Aïssatou Diawara et al.
The American journal of tropical medicine and hygiene, 88(6), 1052-1061 (2013-03-06)
In endemic countries with soil-transmitted helminths mass drug administration with albendazole or mebendazole are being implemented as a control strategy. However, it is well known in veterinary helminths that the use of the same benzimidazole drugs can place selection on

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