PHR1277
依地酸盐二钠杂质A
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
次氮基三乙酸, N,N-二(羧甲基)甘氨酸, NTA, 三(羧甲基)胺
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线性分子式:
N(CH2COOH)3
化学文摘社编号:
分子量:
191.14
Beilstein:
1710776
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1463950
API类
edta
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
245 °C (dec.) (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
OC(=O)CN(CC(O)=O)CC(O)=O
InChI
1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)
InChI key
MGFYIUFZLHCRTH-UHFFFAOYSA-N
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一般描述
次氮基三乙酸（NTA）是一种多氨基多羧酸，它是一种应用广泛的合成螯合剂。它可以和不同的金属形成稳定的水溶性螯合物。它也可用作软化水的洗涤剂助剂，并用于掩盖各种工业过程中的金属离子。
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
应用
一种优质的螯合剂。
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Nitrilotriacetic acid can be used as an internal standard in the determination of nitrilotriacetic acid in water.
Nitrilotriacetic acid can be used as an internal standard in the determination of nitrilotriacetic acid in water.
分析说明
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
其他说明
在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。
想要查看本品的分析证书示例，请在下框中输入LRAC3702。这只是一个示例证书，可能与您收到的批次不符。
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
212.0 °F - closed cup
闪点(°C)
100 °C - closed cup
Determination of nitrilotriacetic acid and ethylenediaminetetraacetic acid in environmental samples as their methyl ester derivatives by gas chromatography-mass spectrometry
Nishikawa Y and Okumura T
Journal of Chromatography A, 690(1), 109-118 (1995)
Quantitative gas chromatographic determination of nitrilotriacetic acid in the presence of other carboxylic acids
Larson RA, et al.
Journal of Chromatography A, 111(1), 43-49 (1975)
Determination of the solubility products of nitrilotriacetic acid, ethylenediaminetetraacetic acid and diethylenetriaminepentaacetic acid.
Karhu J, et al.
Analytica Chimica Acta, 380(1), 105-111 (1999)
The determination of part-per-billion levels of citric and nitrilotriacetic acids in tap water and sewage effluents
Aue WA, et al.
Journal of Chromatography A, 72(2), 259-267 (1972)
Asgar Abbas Kazrani et al.
Nucleic acids research, 42(9), 5929-5936 (2014-03-19)
PvuRts1I is a prototype for a larger family of restriction endonucleases that cleave DNA containing 5-hydroxymethylcytosine (5hmC) or 5-glucosylhydroxymethylcytosine (5ghmC), but not 5-methylcytosine (5mC) or cytosine. Here, we report a crystal structure of the enzyme at 2.35 Å resolution. Although
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