PHR1271
左多巴
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
左旋多巴, 3-(3,4-二羟基苯基)-L-丙氨酸, 3-羟基-L-酪氨酸, L-DOPA, 左多巴
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
(HO)2C6H3CH2CH(NH2)CO2H
化学文摘社编号:
分子量:
197.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-445-2
Beilstein/REAXYS Number:
2215169
MDL number:
产品名称
左多巴, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
WTDRDQBEARUVNC-LURJTMIESA-N
InChI
1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1
SMILES string
N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. L0400000
traceable to USP 1361009
API family
levodopa
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
276-278 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
Gene Information
human ... DRD3(1814)
正在寻找类似产品? 访问 产品对比指南
Analysis Note
这些二级标准品可追溯至USP、EP（PhEur）和BP一级标准品。
Application
左旋多巴可作为药物参考标准品，用于通过流动注射分光光度法和1H核磁共振波谱法对药物制剂中的分析物进行定量。
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
General description
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。左旋多巴是神经递质多巴胺的代谢前体，被广泛应用于帕金森′病的治疗。
Other Notes
想要查看本品的分析证书示例，请在下框中输入LRAC2957。这只是一个示例证书，可能与您收到的批次不符。
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
1H nuclear magnetic resonance spectroscopy analysis for simultaneous determination of levodopa, carbidopa and methyldopa in human serum and pharmaceutical formulations
Talebpour Z, et al.
Analytica Chimica Acta, 506(1), 97-104 (2004)
Handbook of Parkinson's Disease
Parkinson's Disease and Related Disorders, 506(4), 97-104 (2007)
Parkinson's Disease and Related Disorders, 506(1), 97-104 (2006)
L H Marcolino-Júnior et al.
Journal of pharmaceutical and biomedical analysis, 25(3-4), 393-398 (2001-05-30)
A flow injection spectrophotometric procedure was developed for determining levodopa in tablets. The determination of this drug was carried out by reacting it with lead(IV) dioxide immobilized in polyester resin packed in a solid-phase reactor and the dopachrome yielded was
A P de Jong et al.
Clinica chimica acta; international journal of clinical chemistry, 171(1), 49-61 (1988-01-15)
L-3-(3,4-Dihydroxyphenyl)alanine (DOPA) and its 3-O-methyl metabolite (OMD) were measured in plasma and cerebrospinal fluid by a new assay which combines N,O-acetylation of amino acids in aqueous media, preparation of pentafluorobenzyl esters under anhydrous conditions, and analysis by gas chromatography-electron capture
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持