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Merck
CN
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主要文件

PHR1256

Supelco

硫酸阿巴卡韦

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

硫酸阿巴卡韦 硫酸酯

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About This Item

经验公式（希尔记法）:
C28H36N12O2 · H2SO4
CAS号:
188062-50-2
分子量:
670.74
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. Y0001561
traceable to USP 1000408

API类

abacavir

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

[S](=O)(=O)([O-])[O-].[n+]6(c7nc(nc(c7[nH]c6)NC8CC8)N)[C@@H]5C[C@@H](C=C5)CO.[n+]2(c3nc(nc(c3[nH]c2)NC4CC4)N)[C@@H]1C[C@@H](C=C1)CO

InChI

1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1

InChI key

WMHSRBZIJNQHKT-FFKFEZPRSA-N

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相关类别

一般描述

Abacavir sulfate belongs to the class of human immunodeficiency virus (HIV) medicines called nucleoside reverse transcriptase inhibitors, with antiretroviral activity against HIV.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Abacavir sulfate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-peformance liquid chromatography technique and spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3642 in the slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

1000485

Abacavir Related Compounds Mixture, United States Pharmacopeia (USP) Reference Standard

1000496

Abacavir Stereoisomers Mixture, United States Pharmacopeia (USP) Reference Standard

1000500

Abacavir System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

1000408

硫酸阿巴卡韦 硫酸酯, United States Pharmacopeia (USP) Reference Standard

1000419

Abacavir sulfate racemic, United States Pharmacopeia (USP) Reference Standard

1000420

Abacavir Related Compound A, United States Pharmacopeia (USP) Reference Standard

1000441

Abacavir Related Compound B, United States Pharmacopeia (USP) Reference Standard

1000452

Abacavir Related Compound C, United States Pharmacopeia (USP) Reference Standard

Y0001561

硫酸阿巴卡韦 硫酸酯, European Pharmacopoeia (EP) Reference Standard

Y0001551

阿巴卡韦, European Pharmacopoeia (EP) Reference Standard

Y0001552

阿巴卡韦, European Pharmacopoeia (EP) Reference Standard

1000437

Abacavir Related Compound D, United States Pharmacopeia (USP) Reference Standard

BP1112

硫酸阿巴卡韦 硫酸酯, British Pharmacopoeia (BP) Reference Standard

BP1113

阿巴卡韦杂质标准品, British Pharmacopoeia (BP) Reference Standard

BP1114

Abacavir Impurity 1, British Pharmacopoeia (BP) Reference Standard

PHR2064

阿巴卡韦相关化合物A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2074

Abacavir Impurity F, pharmaceutical secondary standard, certified reference material

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Warning

危险分类

Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Spectrophotometric methods for the determination of abacavir sulphate in pharmaceutical preparations
Srihari G
Global Journal of Pharmacology, 5(3), 172-175 (2011)
Determination of abacavir, lamivudine and zidovudine in pharmaceutical tablets, human serum and in drug dissolution studies by HPLC
Savaser A, et al.
Chromatographia, 65(5-6), 259-265 (2007)

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