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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1151709
蒸汽密度
4.1 (vs air)
蒸汽压
8 mmHg ( 20 °C)
9.7 mmHg ( 37.7 °C)
API类
cumene
CofA
current certificate can be downloaded
自燃温度
797 °F
expl. lim.
6.5 %
技术
HPLC: suitable
gas chromatography (GC): suitable
折射率
n20/D 1.491 (lit.)
沸点
152-154 °C (lit.)
mp
−96 °C (lit.)
密度
0.864 g/mL at 25 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-30°C
SMILES字符串
CC(C)c1ccccc1
InChI
1S/C9H12/c1-8(2)9-6-4-3-5-7-9/h3-8H,1-2H3
InChI key
RWGFKTVRMDUZSP-UHFFFAOYSA-N
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一般描述
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
Cumene may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA9023 in the slot below. This is an example certificate only and may not be the lot that you receive.
警示用语：
Danger
危险分类
Aquatic Chronic 2 - Asp. Tox. 1 - Carc. 1B - Flam. Liq. 3 - STOT SE 3
靶器官
Respiratory system
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
87.8 °F - closed cup
闪点(°C)
31.0 °C - closed cup
法规信息
危险化学品
A novel peroxy radical based oxidative stressing system for ranking the oxidizability of drug substances
Harmon PA. et al.
Journal of Pharmaceutical Sciences, 95(9), 2014-2028 (2006)
Determination of Residual Solvents in Bulk Drug and Formulations
Singh P and Sinha M
American Journal of PharmTech Research, 3(4), 289-295 (2006)
C Holvoet et al.
Die Pharmazie, 62(2), 126-132 (2007-03-08)
Paclitaxel, an antitumoral drug, is poorly soluble in aqueous media. Therefore, in a commercialised formulation (Taxol), paclitaxel (30 mg active compound) is dissolved in polyethoxylated castor oil (Cremophor EL) and ethanol. After dilution of Taxol in aqueous media paclitaxel tends
Mathieu Frenette et al.
Journal of the American Chemical Society, 128(51), 16432-16433 (2006-12-21)
A new class of thermally activated chain-breaking antioxidants is presented. Dimers of persistent carbon-centered radicals are able to inhibit the autoxidation of cumene and styrene with better rate constants than the commercial antioxidant Irganox HP-136 and 3,5-di-tert-butyl-4-hydroxyanisole. A dramatic increase
Johanna Bråred Christensson et al.
Contact dermatitis, 55(4), 230-237 (2006-09-09)
Concomitant positive reactions to colophonium, oxidized limonene, and/or oxidized linalool are recorded in patch test studies. The main allergens in these patch test mixtures are hydroperoxides, which form antigens by a radical pathway. Theoretically, concomitant reactions can be explained not
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