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PHR1200

Supelco

氯己定杂质P

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-氯苯胺

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About This Item

线性分子式:
ClC6H4NH2
CAS号:
106-47-8
分子量:
127.57
Beilstein:
471359
EC 号:
203-401-0
MDL编号:
MFCD00007835
UNSPSC代码:
41116107
PubChem化学物质编号:
329823207
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1111908

蒸汽密度

4.4 (vs air)

蒸汽压

0.15 mmHg ( 25 °C)

API类

proguanil, chlorhexidine 

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

沸点

232 °C (lit.)

mp

67-70 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

Nc1ccc(Cl)cc1

InChI

1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI key

QSNSCYSYFYORTR-UHFFFAOYSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

p-Chloroaniline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3328 in the slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

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1568073

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Proguanil Related Compound A, United States Pharmacopeia (USP) Reference Standard

1568051

Proguanil Related Compound C, United States Pharmacopeia (USP) Reference Standard

1568062

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1568084

Proguanil Related Compound F, United States Pharmacopeia (USP) Reference Standard

1568095

Proguanil Related Compound G, United States Pharmacopeia (USP) Reference Standard

1111908

4-氯苯胺, United States Pharmacopeia (USP) Reference Standard

PHR1713

盐酸氯胍, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001901

氯胍 盐酸盐, European Pharmacopoeia (EP) Reference Standard

BP297

氯胍 盐酸盐, British Pharmacopoeia (BP) Reference Standard

PHR3115

Proguanil Related Compound A, pharmaceutical secondary standard, certified reference material

PHR3116

Proguanil Related Compound C, pharmaceutical secondary standard, certified reference material

PHR3117

Proguanil Related Compound E, pharmaceutical secondary standard, certified reference material

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Skin Sens. 1

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

248.0 °F - closed cup

闪点(°C)

120.0 °C - closed cup

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Preparation and evaluation of lidocaine hydrochloride in cyclodextrin inclusion complexes for development of stable gel in association with chlorhexidine gluconate for urogenital use
da Silva LFJS, et al.
International journal of nanomedicine, 6(3), 1143-1143 (2011)
HPLC determination of chlorhexidine gluconate and p-chloroaniline in topical ointment
Havlikova L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1169-1173 (2007)
D Mortenson et al.
International endodontic journal, 45(9), 878-882 (2012-04-11)
To determine if the formation of para-chloroaniline (PCA) can be avoided by using an alternative irrigant following sodium hypochlorite but before chlorhexidine. Fifty-five single-rooted teeth were decoronated, instrumented to size 40, .06 taper whilst being irrigated with 14% ethylene-diamine-tetra-acetic acid
Fabio Gosetti et al.
Environmental pollution (Barking, Essex : 1987), 158(2), 592-598 (2009-09-22)
This paper studies the degradation reactions that 4-chloroaniline can naturally undergo in waters for the action of sun light. 10.00 mg L(-1) 4-chloroaniline aqueous solution, without any addition of organic solvent, are undergone to photoirradiation under conditions that simulate sun
Kun Yang et al.
Environmental science & technology, 44(8), 3021-3027 (2010-03-06)
Competitive adsorption between nonpolar organic compounds and polar ionic organic compounds (IOCs) on carbon nanotubes (CNTs) is essential for application of CNTs as superior sorbents and for environmental risk assessment of both CNTs and organic contaminants. It was observed in
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