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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

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主要文件

PHR1197

Supelco

5H-二苯并[b,f]氮杂

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

卡马西平相关化合物B, 亚氨基芪

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About This Item

经验公式(希尔记法):
C14H11N
CAS号:
分子量:
193.24
Beilstein:
1343358
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to USP 1093023

API类

carbamazepine, oxcarbazepine 

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

196-199 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

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此商品
F0504M1891C4874
biological source

bovine

biological source

bovine milk

biological source

bovine

biological source

bovine

technique(s)

immunofluorescence: suitable

technique(s)

ligand binding assay: suitable, surface plasmon resonance (SPR): suitable

technique(s)

activity assay: suitable

technique(s)

-

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

UniProt accession no.

P81282

UniProt accession no.

-

UniProt accession no.

P02687

UniProt accession no.

P62157

Gene Information

cow ... VCAN(282662)

Gene Information

-

Gene Information

cow ... MBP(618684)

Gene Information

bovine ... CALM(100297344)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards..

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA9013 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Exclamation markEnvironment

警示用语:

Warning

危险声明

预防措施声明

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

  • 技术规格说明书

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Koleta Hemine et al.
    Carbohydrate polymers, 250, 116957-116957 (2020-10-15)
    It is widely believed that the hydrophobic effect governs the binding of guest molecules to cyclodextrins (CDs). However, it is also known that high hydrophobicity of guest molecules does not always translate to the formation of stable inclusion complexes with
    S M Furst et al.
    Drug metabolism and disposition: the biological fate of chemicals, 23(5), 590-594 (1995-05-01)
    Carbamazepine therapy is associated with several types of idiosyncratic drug reactions, including hematological disorders. In previous studies, we found that carbamazepine was metabolized by the myeloperoxidase/H2O2 system of activated neutrophils, and covalent binding of the drug to neutrophils was observed.
    B Moosmann et al.
    Biological chemistry, 382(11), 1601-1612 (2002-01-05)
    Oxidative stress is a widespread phenomenon in the pathology of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Neuronal cell death due to oxidative stress may causally contribute to the pathogeneses of these diseases. Therefore, neuroprotective
    T M Li et al.
    Epilepsia, 23(4), 391-398 (1982-08-01)
    Carbamazepine is an anticonvulsant drug useful in the management of epilepsy. Because of the narrow therapeutic range, serum carbamazepine monitoring is useful for ensuring adequate drug therapy without toxicity. We report the development of a homogeneous substrate-labeled fluorescent immunoassay for
    Predrag Lj Dzodić et al.
    Journal of AOAC International, 93(4), 1059-1068 (2010-10-07)
    An accurate and precise RP-HPLC method was developed and validated for the determination of carbamazepine and its impurities iminostilbene and iminodibenzyl in a tablet formulation with fluphenazine as an internal standard. Buffer-methanol (50 + 50, v/v) was used as the

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