PHR1197
5H-二苯并[b,f]氮杂
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
卡马西平相关化合物B, 亚氨基芪
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H11N
化学文摘社编号:
分子量:
193.24
Beilstein/REAXYS Number:
1343358
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-970-0
MDL number:
产品名称
5H-二苯并[b,f]氮杂, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H
InChI key
LCGTWRLJTMHIQZ-UHFFFAOYSA-N
SMILES string
N1c2ccccc2C=Cc3ccccc13
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1093023
API family
carbamazepine, oxcarbazepine
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
196-199 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards..
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9013 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Koleta Hemine et al.
Carbohydrate polymers, 250, 116957-116957 (2020-10-15)
It is widely believed that the hydrophobic effect governs the binding of guest molecules to cyclodextrins (CDs). However, it is also known that high hydrophobicity of guest molecules does not always translate to the formation of stable inclusion complexes with
Ying Wu et al.
The Journal of allergy and clinical immunology, 118(1), 233-241 (2006-07-04)
T-cell-mediated hypersensitivity is a rare but serious manifestation of drug therapy. To explore the mechanisms of drug presentation to T cells and the possibility that generation of metabolite-specific T cells may provoke cross-sensitization between drugs. A lymphocyte transformation test was
S M Furst et al.
Biochemical pharmacology, 45(6), 1267-1275 (1993-03-24)
Carbamazepine is an anticonvulsant which is associated with a significant incidence of hypersensitivity reactions including agranulocytosis. We have postulated that many drug hypersensitivity reactions, especially agranulocytosis and lupus, are due to reactive metabolites generated by the myeloperoxidase (MPO) (EC 1.11.1.7)
A Varenne et al.
Journal of immunological methods, 186(2), 195-204 (1995-10-26)
As part of our ongoing work to extend the range of applications of the non-isotopic carbonyl metalloimmunoassay (CMIA), previously developed in our laboratory, we describe here the first CMIA study of carbamazepine. The CMIA method uses a metal carbonyl complex
S M Furst et al.
Drug metabolism and disposition: the biological fate of chemicals, 23(5), 590-594 (1995-05-01)
Carbamazepine therapy is associated with several types of idiosyncratic drug reactions, including hematological disorders. In previous studies, we found that carbamazepine was metabolized by the myeloperoxidase/H2O2 system of activated neutrophils, and covalent binding of the drug to neutrophils was observed.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持