PHR1196
呋喃西林
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
5-硝基-2-糠醛半卡巴腙, 5-硝基-2-呋喃甲醛半卡腙, NFZ, 呋喃西林, 硝呋醛
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经验公式（希尔记法）:
C6H6N4O4
化学文摘社编号:
分子量:
198.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-443-1
Beilstein/REAXYS Number:
86403
MDL number:
产品名称
呋喃西林, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+
InChI key
IAIWVQXQOWNYOU-FPYGCLRLSA-N
SMILES string
NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. N0950000
traceable to USP 1465004
API family
nitrofurazone
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
242-244 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Application
Nitrofurazone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by DC polarography, chromatography and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0296 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2
target_organs
male reproductive organs
存储类别
11 - Combustible Solids
wgk
WGK 3
Inclusion compounds in pharmaceutical analysis II: Assay of a cream following chemical dehydration
Hays SE and Grady LT
Journal of Pharmaceutical Sciences, 60(2), 295-298 (1971)
Electrochemical reduction of nitrofurazone and its determination in pharmaceutical dosage forms by Dc polarography
Mishra AK and Gode KD
Analyst, 110(11), 1373-1376 (1985)
Teresa del Castillo et al.
ChemMedChem, 9(2), 383-389 (2013-12-18)
Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad hoc synthesis of each cyclodextrin-targeting agent conjugate. We
Yongnian Ni et al.
Biosensors & bioelectronics, 38(1), 245-251 (2012-06-22)
Electrochemical behavior of nitrofurazone (NFZ) was investigated with the use of cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. The pH-dependence of NFZ was studied at a glassy carbon electrode (GCE) in ethanol/Britton-Robinson buffer (30:70), and short-lived nitro-radicals were
James R Johnson et al.
The Journal of urology, 184(6), 2572-2577 (2010-10-30)
We determined the activity, comparative potency and effect durability of commercially available, antimicrobial coated Foley catheters against Escherichia coli isolates, including extended spectrum cephalosporin resistant strains. We used an inhibition zone assay (diffusible inhibition) and an adherence assay (diffusible and
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