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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1680608
API类
tributyl acetylcitrate
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
折射率
n20/D 1.445
密度
1.043 g/mL at 20 °C (lit.)
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-30°C
SMILES字符串
CCCCOC(=O)CC(O)(CC(=O)OCCCC)C(=O)OCCCC
InChI
1S/C18H32O7/c1-4-7-10-23-15(19)13-18(22,17(21)25-12-9-6-3)14-16(20)24-11-8-5-2/h22H,4-14H2,1-3H3
InChI key
ZFOZVQLOBQUTQQ-UHFFFAOYSA-N
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一般描述
Tributyl citrate is an ester of citric acid. It is used to plasticize polymers for coating solid drug dosage forms, tablets and capsules.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.
附注
To see an example of a Certificate of Analysis for this material enter LRAA8989 in the slot below. This is an example certificate only and may not be the lot that you receive.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Handbook of Pharmaceutical Excipients, 1 (2006)
Eva Roblegg et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(3), 635-645 (2011-08-02)
The objective of this study was the development of retarded release pellets using vegetable calcium stearate (CaSt) as a thermoplastic excipient. The matrix carrier was hot melt extruded and pelletized with a hot-strand cutter in a one step continuous process.
Bernadette Pretzl et al.
Journal of clinical periodontology, 36(4), 349-356 (2009-05-12)
Evaluation of the 10-year results after GTR-therapy of infrabony defects using two bioabsorbable barriers in a randomized-controlled clinical trial. In 15 patients with periodontitis, 15 pairs of infrabony defects were treated. For each patient, one defect received a polydioxanon (test:
P Eickholz et al.
Journal of periodontology, 71(6), 999-1008 (2000-07-29)
The aim of this study was to compare the effects of guided tissue regeneration (GTR) using 2 different bioabsorbable barriers (control: polylactide acetyltributyl citrate; test: polydioxanon). The polydioxanon barrier is an experimental membrane for GTR therapy that consists of a
Werner Schroth et al.
Marine biotechnology (New York, N.Y.), 7(5), 449-461 (2005-06-25)
We describe a strategy that identifies molecular biomarkers and links the study of abiotic stress to evolutionary history. By utilizing the moon jellyfish Aurelia spp. as a model, we identified genes differentially regulated in response to the chemical stressor tributyltin
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