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PHR1126

磺胺甲噁唑

Name: 磺胺甲噁唑
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-氨基- N -（5-甲基-3-异恶唑基）苯磺酰胺, N ¹-（5-甲基异恶唑-3-基）磺胺

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About This Item

经验公式（希尔记法）:

C₁₀H₁₁N₃O₃S

CAS号:

723-46-6

分子量:

253.28

Beilstein:

6732984

EC 号:

211-963-3

MDL编号:

MFCD00010546

UNSPSC代码:

41116107

PubChem化学物质编号:

329823147

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 314
traceable to Ph. Eur. S2100000
traceable to USP 1631001

API类

sulfamethoxazole

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

InChI key

JLKIGFTWXXRPMT-UHFFFAOYSA-N

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一般描述

用于质量控制的已认证的药物二级标准品，为制药实验室和制造商提供了药典基本标准的一种方便且成本效益好的替代品。
磺胺甲恶唑是治疗人类泌尿系统感染最有效的磺胺类药物之一。

应用

磺胺甲恶唑可作为药物参考标准品，通过方波伏安法以及可见光和紫外分光光度技术对药物制剂中的分析物进行测定。

这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可追溯至USP、EP（PhEur）和BP一级标准品。

其他说明

该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。

附注

想要查看本品的检验报告示例，请在下框中输入LRAA6910。这只是一个示例证书，可能与您收到的批次不符。

警示用语：

Warning

危险声明

H361fd,H411

预防措施声明

P202 - P273 - P280 - P308 + P313 - P391 - P405

危险分类

Aquatic Chronic 2 - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

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分析证书(COA)

Lot/Batch Number

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Determination of sulfamethoxazole and trimethoprim in pharmaceuticals by visible and UV spectrophotometry.

Shamsa F and Amani L

Iranian Journal of Pharmaceutical Research : IJPR, 31-36 (2010)

Electroanalytical determination of sulfadiazine and sulfamethoxazole in pharmaceuticals using a boron-doped diamond electrode.

Souza CD, et al.

Sensors and Actuators B, Chemical, 135(1), 66-73 (2008)

Sorption of antibiotic sulfamethoxazole varies with biochars produced at different temperatures.

Hao Zheng et al.

Environmental pollution (Barking, Essex : 1987), 181, 60-67 (2013-07-03)

Sorption of sulfonamides on biochars is poorly understood, thus sulfamethoxazole (SMX) sorption on biochars produced at 300-600 °C was determined as a function of pH and SMX concentration, as well as the inorganic fractions in the biochars. Neutral SMX molecules

Impact of humic acid fouling on membrane performance and transport of pharmaceutically active compounds in forward osmosis.

Ming Xie et al.

Water research, 47(13), 4567-4575 (2013-06-15)

The impact of humic acid fouling on the membrane transport of two pharmaceutically active compounds (PhACs) - namely carbamazepine and sulfamethoxazole - in forward osmosis (FO) was investigated. Deposition of humic acid onto the membrane surface was promoted by the

Prevalence of sulfonamide-resistant bacteria, resistance genes and integron-associated horizontal gene transfer in natural water bodies and soils adjacent to a swine feedlot in northern Taiwan.

Jih-Tay Hsu et al.

Journal of hazardous materials, 277, 34-43 (2014-03-19)

Antibiotics are commonly used in swine feed to treat and prevent disease, as well as to promote growth. Antibiotics released into the environment via wastewater could accelerate the emergence of antibiotic-resistant bacteria and resistance genes in the surrounding environment. In

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