PHR1126
磺胺甲噁唑
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
4-氨基- N -（5-甲基-3-异恶唑基）苯磺酰胺, N 1 -（5-甲基异恶唑-3-基）磺胺
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关于此项目
经验公式（希尔记法）:
C10H11N3O3S
化学文摘社编号:
分子量:
253.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
211-963-3
Beilstein/REAXYS Number:
6732984
MDL number:
InChI key
JLKIGFTWXXRPMT-UHFFFAOYSA-N
InChI
1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
SMILES string
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
grade
certified reference material, pharmaceutical secondary standard
agency
USP 1631001, traceable to Ph. Eur. S2100000
API family
sulfamethoxazole
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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General description
用于 质量控制的认证药物二级标准品为 制药实验室和制造商提供了一种方便且具有成本效益 的主要标准替代品磺胺甲恶唑是用于治疗人类泌尿道感染的最有效的磺胺类药物之一。
Application
磺胺甲恶唑可作为药物参考标准品，通过方波伏安法以及可见光和紫外分光光度技术对药物制剂中的分析物进行测定。
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
想要查看本品的检验报告示例，请在下框中输入LRAA6910。这只是一个示例证书，可能与您收到的批次不符。
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Repr. 2
存储类别
11 - Combustible Solids
Determination of sulfamethoxazole and trimethoprim in pharmaceuticals by visible and UV spectrophotometry.
Shamsa F and Amani L
Iranian Journal of Pharmaceutical Research : IJPR, 31-36 (2010)
Electroanalytical determination of sulfadiazine and sulfamethoxazole in pharmaceuticals using a boron-doped diamond electrode.
Souza CD, et al.
Sensors and Actuators B, Chemical, 135(1), 66-73 (2008)
Ming Xie et al.
Water research, 47(13), 4567-4575 (2013-06-15)
The impact of humic acid fouling on the membrane transport of two pharmaceutically active compounds (PhACs) - namely carbamazepine and sulfamethoxazole - in forward osmosis (FO) was investigated. Deposition of humic acid onto the membrane surface was promoted by the
Hao Zheng et al.
Environmental pollution (Barking, Essex : 1987), 181, 60-67 (2013-07-03)
Sorption of sulfonamides on biochars is poorly understood, thus sulfamethoxazole (SMX) sorption on biochars produced at 300-600 °C was determined as a function of pH and SMX concentration, as well as the inorganic fractions in the biochars. Neutral SMX molecules
Alexandra G Gonçalves et al.
Journal of hazardous materials, 239-240, 167-174 (2012-09-27)
Two carbon materials (multi-walled carbon nanotubes, MWCNTs, and activated carbon) were investigated as ozonation catalysts for the mineralization of the antibiotic sulphamethoxazole (SMX). MWCNTs presented a higher catalytic performance than activated carbons, which was justified by their differences in surface
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