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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1635002
API类
sulfapyridine
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
~Approximately 191 °C
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-30°C
SMILES字符串
Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2
InChI
1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)
InChI key
GECHUMIMRBOMGK-UHFFFAOYSA-N
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一般描述
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfapyridine melting point standard, also called Sulfapyridine, is a metabolite of sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis. Sulfapyridine is a short acting sulfonamide, which can be substituted for dapsone and it does not cause neuropathy.
Sulfapyridine Melting Point Standard also called Sulfapyridine is a metabolite of Sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA7140 in the slot below. This is an example certificate only and may not be the lot that you receive.
警示用语：
Warning
危险声明
危险分类
Repr. 2
WGK
WGK 2
Clinical Dermatology E-Book (2009)
Christopher Chidley et al.
Nature chemical biology, 7(6), 375-383 (2011-04-19)
We introduce an approach for detection of drug-protein interactions that combines a new yeast three-hybrid screening for identification of interactions with affinity chromatography for their unambiguous validation. We applied the methodology to the profiling of clinically approved drugs, resulting in
Cemalettin Alp et al.
Journal of enzyme inhibition and medicinal chemistry, 27(6), 818-824 (2011-12-23)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I, II and human serum isozyme VI, with a series of tosylited aromatic amine derivatives was investigated. The K(I) ranges of compounds 1-14 and acetazolamide against hCA I
Hai Haham et al.
Environmental science & technology, 46(21), 11870-11877 (2012-10-02)
Sorption-desorption behavior of sulfapyridine was studied with three distinct soil types low in organic carbon with or without the introduction of exogenous dissolved organic matter (DOM). Experiments with bulk soils yielded sorption coefficients equivalent to those obtained with soils richer
Amirali Popat et al.
Angewandte Chemie (International ed. in English), 51(50), 12486-12489 (2012-11-07)
I want to break free: Mesoporous silica nanoparticles are functionalized with sulfasalazine (SZ; see scheme), a prodrug of 5-aminosalicylic acid (5-ASA) and sulfapyridine, to generate enzyme-responsive nanocarriers. In the presence of the colon-specific enzyme azo-reductase (orange), 5-ASA and sulfapyridine are
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