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Merck
CN

PHR1085

胡莫柳酯

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

水杨酸 3,3,5-三甲基环己基酯, 2-羟基苯甲酸 3,3,5-三甲基环己基酯, 水杨酸三甲环己酯, 胡莫柳酯

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关于此项目

经验公式(希尔记法):
C16H22O3
化学文摘社编号:
分子量:
262.34
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
204-260-8
Beilstein/REAXYS Number:
2731604
MDL number:
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InChI key

WSSJONWNBBTCMG-UHFFFAOYSA-N

InChI

1S/C16H22O3/c1-11-8-12(10-16(2,3)9-11)19-15(18)13-6-4-5-7-14(13)17/h4-7,11-12,17H,8-10H2,1-3H3

SMILES string

CC1CC(CC(C)(C)C1)OC(=O)c2ccccc2O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1311408

API family

homosalate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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General description

胡莫柳酯(Homosalate)是一种紫外线过滤剂,可保护皮肤免受UVB(280-315 nm)和UVA II(315-340 nm)辐射的有害影响。它被广泛用于化妆品、防晒霜和局部用药配方中。
用于质量控制的药物二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

Application

胡莫柳酯可用作药物参考标准品,用于通过色谱技术测定药物制剂中的分析物。
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

想要查看本品的分析证书示例,请在下框中输入LRAC3174。这只是一个示例证书,可能与您收到的批次不符。
本有证标准物质 (CRM) 按照 ISO 17034 ISO/IEC 17025 生产和认证。有关本 CRM 使用的所有信息,请参见检验报告。

存储类别

10 - Combustible liquids

flash_point_f

339.4 °F - closed cup

flash_point_c

170.8 °C - closed cup


分析证书(COA)

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Supercritical fluid extraction and high performance liquid chromatography determination of homosalate in lipsticks
Salvador A, et al.
Chromatographia, 54(11-12), 795-797 (2001)
Homosalate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 37(2), 2163-2163 (2013)
Yufeng Zhang et al.
Journal of chromatography. A, 1271(1), 56-61 (2012-12-15)
In the present study, a rapid, highly efficient and environmentally friendly sample preparation method named temperature-controlled ionic liquid dispersive liquid-phase microextraction (TC-IL-DLPME), followed by high performance liquid chromatography (HPLC) was developed for the extraction, preconcentration and determination of four benzophenone-type
Benjamin Choquenet et al.
Journal of natural products, 71(6), 1117-1118 (2008-06-03)
Given that flavonoids are known for their ultraviolet (UV)B photoprotective properties in plants that contain them, we chose to study quercetin (1) and rutin (2) as agents that could potentially be used in sunscreen products. These two substances proved to
Rapid analysis of ultraviolet filters using dispersive liquid-liquid microextraction coupled to headspace gas chromatography and mass spectrometry
Pierson SA, et al.
Journal of Separation Science, 41(15), 3081-3088 (2018)

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