所有图片(1)
别名:
(±)1-(异丙氨基)-3-[p-(β-甲氧基乙基)苯氧基] -2-丙醇 (+)-酒石酸盐, Lopressor
线性分子式:
(C15H25NO3)2 · C4H6O6
CAS号:
分子量:
684.81
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
推荐产品
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to BP 540
traceable to Ph. Eur. M1830000
traceable to USP 1441301
API类
metoprolol
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
储存温度
2-30°C
SMILES字符串
O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2
InChI
1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1
InChI key
YGULWPYYGQCFMP-CEAXSRTFSA-N
基因信息
human ... ADRB1(153)
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一般描述
Metoprolol Tartrate is a β-blocking drug, showing antihypertensive and anti-ischemic effects. It is widely used in the treatment of hypertension and helps in controlling ventricular response in patients with atrial fibrillation.
应用
Metoprolol Tartrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using densitometric technique and spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA6905 in the slot below. This is an example certificate only and may not be the lot that you receive.
相关产品
产品编号
说明
价格
警示用语：
Warning
危险声明
危险分类
Aquatic Chronic 2 - Repr. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Current Cardiovascular Drugs, 15(4), 581-585 (2005)
A validated HPLC method for estimation of metoprolol in human plasma
Aqil M, et al.
Acta Chromatographica , 19, 130-130 (2007)
Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms
Vujic Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15(5), 581-585 (1997)
AAS and spectrophotometric determination of propranolol HCl and metoprolol tartrate
El-Ries MA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 24(2), 179-187 (2000)
Thomas Kahan et al.
European journal of clinical investigation, 43(2), 141-151 (2013-01-03)
Although stable angina pectoris often carries a favourable prognosis, it remains important to identify patients with an increased risk of cardiovascular (CV) complications. Many new markers of disease activity and prognosis have been described. We evaluated whether common and easily
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