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Merck
CN

PHR1054

核黄素

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(−)-核黄素, 乳黄素, 维生素 B2, 维生素 G

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关于此项目

经验公式(希尔记法):
C17H20N4O6
化学文摘社编号:
分子量:
376.36
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
34058005
UNSPSC Code:
41116107
EC Number:
201-507-1
MDL number:
Beilstein/REAXYS Number:
97825
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产品名称

核黄素, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

AUNGANRZJHBGPY-SCRDCRAPSA-N

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

SMILES string

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. R060000
traceable to USP 1603006

API family

riboflavin

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

290 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

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Application

核黄素可作为参考标准品,用于通过各种色谱技术测定熟香肠和能量饮料中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

General description

用于质量控制的经认证的药物二级标准为制药实验室和制造商提供了一种方便且具有成本效益的内部工作标准品替代品。

Other Notes

想要查看本品的分析证书示例,请在下框中输入LRAC0268。这只是一个示例证书,可能与您收到的批次不符。
该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Rapid method for determination of riboflavin in urine by high-performance liquid chromatography
Smith DM, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 182(3), 285-291 (1980)
Determination of total riboflavin in cooked sausages
Valls F, et al.
Journal of Agricultural and Food Chemistry, 47(3), 1067-1070 (1999)
Simultaneous determination of riboflavin, pyridoxine, nicotinamide, caffeine and taurine in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry
Aranda M and Morlock G
Journal of Chromatography A, 1131(1-2), 253-260 (2006)
Zisis Gatzioufas et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(12), 846-848 (2013-10-31)
To investigate the effect of high-fluence corneal collagen cross-linking (CXL) with riboflavin and ultraviolet-A in the management of progressive keratoconus. Preliminary results from a prospective cohort study. Seven eyes from 7 patients with progressive keratoconus subjected to CXL were included.
Carol P Wilson et al.
Hypertension (Dallas, Tex. : 1979), 61(6), 1302-1308 (2013-04-24)
Intervention with riboflavin was recently shown to produce genotype-specific lowering of blood pressure (BP) in patients with premature cardiovascular disease homozygous for the 677C→T polymorphism (TT genotype) in the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR). Whether this effect is

商品

Learn to separate and quantify B vitamins and preservatives in capsules with HPLC-UV and Purospher® STAR RP-8 column. Validated for precision.

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