等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to BP 458
traceable to Ph. Eur. P4100000
traceable to USP 1587001
API类
pyridoxine
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
214-215 °C (lit.)
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-30°C
SMILES字符串
Cl[H].Cc1ncc(CO)c(CO)c1O
InChI
1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
InChI key
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
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一般描述
盐酸吡哆醇是一种水溶性维生素，广泛用于预防异烟肼治疗引起的周围神经病变和中枢神经系统影响。它是血红蛋白形成的必需组分，也参与糖类、脂肪和氨基酸代谢。
应用
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他标定应用。
盐酸吡哆醇可作为药物参考标准品，通过反相高效液相色谱和分光光度技术测定药物制剂中的分析物。
分析说明
这些二级标准品可多次溯源至美国药典、欧洲药典和英国药典一级标准品（如可用）。
其他说明
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
附注
要查看该材料的检验报告示例，请在下面的插槽中输入 LRAB3720。这只是一个示例证书，可能不是您收到的批次。
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相关产品
产品编号
说明
价格
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous derivative spectrophotometric analysis of doxylamine succinate, pyridoxine hydrochloride and folic acid in combined dosage forms
Pathak A and Rajput JS
Indian Journal of Pharmaceutical Sciences, 70(4), 513-513 (2008)
Development and validation of RP-HPLC method for simultaneous determination of pyridoxine hydrochloride, isoniazid, pyrazinamide and rifampicin in pharmaceutical formulation
Dhal KS and Sharma R
Chem. Anal. (Warsaw), 54(6), 1487-1487 (2009)
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin
Manfred Eggersdorfer et al.
Angewandte Chemie (International ed. in English), 51(52), 12960-12990 (2012-12-05)
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized to be curable with an adequate diet. These diseases had been prevalent
实验方案
Separation of Pyridoxine Hydrochloride (B6), analytical standard; Thiamine Hydrochloride (B1), analytical standard
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