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Merck
CN

PHR1010

Supelco

羟苯丙酯

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-羟基苯甲酸丙酯, 对羟基安息香酸丙酯, 尼泊金丙酯

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About This Item

线性分子式:
HOC6H4CO2CH2CH2CH3
CAS号:
分子量:
180.20
Beilstein:
1103245
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
E编号:
E216
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. P3650000
traceable to USP 1577008

API类

parabens

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

95-98 °C (lit.)

应用

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

CCCOC(=O)c1ccc(O)cc1

InChI

1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3

InChI key

QELSKZZBTMNZEB-UHFFFAOYSA-N

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一般描述

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。羟苯丙酯是一种苯甲酸酯,广泛用作个人护理产品中的防腐剂。

应用

这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准提供了有效的美国药典、欧洲药典和英国药典一级标准的多重可追溯性。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

想要查看本品的分析证书示例,请在下框中输入LRAC2886。这只是一个示例证书,可能与您收到的批次不符。

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危险声明

预防措施声明

危险分类

Aquatic Chronic 3

WGK

WGK 1

闪点(°F)

356.0 °F

闪点(°C)

180 °C


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分析证书(COA)

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Chemosphere, 226, 388-394 (2019-04-05)
Parabens are used as a preservative substance in a wide range of man-made products causing deleterious effects on aquatic organisms and therefore, the concern of their effects to aquatic organisms has been increased. In this study, acute toxicity of methylparaben
Michelle P Dvores et al.
Langmuir : the ACS journal of surfaces and colloids, 28(17), 6978-6984 (2012-03-29)
This study presents a method for one-step formation of poly(ethylene oxide) nanofibers incorporating nanoparticles of a poorly water-soluble compound. Using the new method reported here, nanofiber-nanoparticle composites are fabricated in one step by electrospinning of an oil-in-water microemulsion, in which
Dennis G Maki et al.
Critical care medicine, 39(4), 613-620 (2011-01-05)
Catheter-related bloodstream infection is the greatest threat to the safety of patients on hemodialysis. Catheter lock solutions containing heparin have been linked to an increased risk of hemorrhage and thrombocytopenia. To ascertain the safety and efficacy for prevention of catheter-related
C L Barberis et al.
Journal of food protection, 73(8), 1493-1501 (2010-09-08)
Each year, a significant portion of the peanuts produced cannot be marketed because of fungal disease at the postharvest stage and mycotoxin contamination. Antioxidants could be used as an alternative to fungicides to control ochratoxigenic fungi in peanuts during storage.
Miguel González-Doncel et al.
Environmental pollution (Barking, Essex : 1987), 184, 360-369 (2013-10-08)
Here we proposed a battery of non-invasive biomarkers and a histological survey to examine physiological/anatomical features in embryos, eleutheroembryos (13 days post-fertilization, dpf), and larvae (28-42 dpf) of medaka to investigate the effects of embryonic exposure to propylparaben (PrP). Concentrations <1000 μg

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