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Merck
CN

PHR1008

Supelco

维生素C

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

L -抗坏血酸, 维他命C, 抗坏血病因子, 维生素C

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About This Item

经验公式(希尔记法):
C6H8O6
CAS号:
分子量:
176.12
Beilstein:
84272
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
E编号:
E300
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to BP 461
traceable to Ph. Eur. A1300000
traceable to USP 1043003

API类

ascorbic acid

形式

solid

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

190-194 °C (dec.)

应用

food and beverages

格式

neat

储存温度

2-8°C

SMILES字符串

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

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一般描述

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。抗坏血酸是一种强大的抗氧化剂,广泛用于药物制剂中。经证其对衰老相关疾病(如癌症、动脉粥样硬化、眼病、神经退行性疾病等)具有有益作用。它主要参与胶原蛋白的形成和维持。饮食长期缺乏抗坏血酸会导致坏血病。

应用

抗坏血酸可用制药参考标准品,通过亲水作用色谱定量药物制剂中的分析物。

生化/生理作用

抗坏血酸,也称为维生素C,是由植物和一些动物物种(不包括人类和其他灵长类动物)产生的六碳内酯。抗坏血酸可作为多种酶的酶促辅助因子,可用作单加氧酶和双加氧酶的电子供体。抗坏血酸还起到强力抗氧化剂的作用,特别是对活性氧。

分析说明

这些二级标准品为USP、EP(PhEur)和BP等主要标准品提供了多种可追溯性。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

想要查看本品的分析证书示例,请在下框中输入LRAC2886。这只是一个示例证书,可能与您收到的批次不符。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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商品

Simultaneous analysis of ascorbic acid and dehydroascorbic acid in various food samples by High Performance Thin Layer Chromatography (HPTLC).

A new RP-HPLC method is proposed for the determination of organic acids in 100% aqueous mobile phase using an Ascentis® Express AQ-C18 column

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