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Merck
CN

PHL82542

Fisetin

phyproof® Reference Substance

别名:

3,3′,4′,7-四羟基黄酮, 5-脱氧槲皮素, Cotinin, Fiestin, Fietin

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About This Item

经验公式(希尔记法):
C15H10O6
CAS号:
分子量:
286.24
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

primary reference standard

产品线

phyproof® Reference Substance

检测方案

≥90.0% (HPLC)

制造商/商品名称

PhytoLab

应用

food and beverages

格式

neat

InChI

1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

InChI key

XHEFDIBZLJXQHF-UHFFFAOYSA-N

一般描述

该物质是具有指定绝对纯度(考虑色谱纯度、水、残留溶剂、无机杂质)的一级参考物质。确切的值见证书。生产商:PhytoLab GmbH & Co. KG

应用

  • Fisetin anti-inflammatory and antioxidative properties: Fisetin reduces inflammation and oxidative stress in deep vein thrombosis, signaling via the MAPK and NRF2 pathways, highlighting its potential as an anti-inflammatory agent and its importance in managing thrombotic disorders (Liu and Lu, 2024).
  • Fisetin in drug delivery system enhancement: A mechanochemical method improves fisetin′s solubility and biological activity, suggesting its utility in creating effective drug delivery systems that enhance the therapeutic effects of fisetin, particularly relevant in flavonoid research for increased bioavailability (Rosiak et al., 2024).
  • Fisetin combination therapy for neuropathic pain: Utilizing fisetin with other treatments like pregabalin and gabapentin shows effectiveness in managing neuropathic pain, demonstrating fisetin′s role in enhancing pain management therapies and its potential in neuropharmacology (Karabacak et al., 2024).
  • Fisetin in neurodegenerative disease research: Fisetin interacts with gut microbiota to offer a novel therapeutic approach in preventing and treating neurodegenerative diseases like Parkinson′s, underscoring its role in neuroprotective dietary interventions and the development of nutraceuticals (Yao et al., 2024).
  • Fisetin in cardiovascular disease management: Fisetin suppresses atherosclerosis in apolipoprotein E knockout mice by inhibiting ferroptosis-related oxidative stress, indicating its potential use as a therapeutic agent in cardiovascular disease through modulation of oxidative stress pathways (Jiang et al., 2024).

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Vanesa A Muñoz et al.
Photochemistry and photobiology, 96(4), 815-825 (2020-01-09)
In this work, the flavonol fisetin was selected in order to study its reactivity against Cu(II), a metal ion of interest in biological media and industry. The stoichiometry and apparent formation constant of the complex in ethanolic medium at 25°C

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