推荐产品
生物来源
synthetic (organic)
质量水平
等级
reagent grade
表单
powder
mp
100-104 °C (lit.)
溶解性
methanol: 200 mM (Stock solution is stable for months at –20° C.)
SMILES字符串
O.c1cnc2c(c1)ccc3cccnc23
InChI
1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2
InChI key
PPQJCISYYXZCAE-UHFFFAOYSA-N
基因信息
human ... FNTA(2339)
正在寻找类似产品? 访问 产品对比指南
一般描述
菲咯啉是一种杂环有机化合物,可与金属离子形成络合物。这些络合物在生物化学、催化和分析化学领域应用广泛。与铁络合,可作为氧化还原指示剂。
应用
1,10-菲咯啉一水合物用于:
- 用作MDA-MB-231乳腺癌细胞金属蛋白酶(MMP)的抑制剂
- 用作小鼠心脏样本原位酶谱分析的阴性对照品
- 体外白藜芦醇螯合以及螯合铁的还原活性测定
当与铜络合时,具有核酸酶活性,用于研究 DNA-蛋白质相互作用。
生化/生理作用
金属蛋白酶抑制剂;可与铁、锌和其他二价金属形成螯合物。有效浓度 1-10mM。
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
从最新的版本中选择一种:
分析证书(COA)
Acta veterinaria Hungarica, 68(1), 79-84 (2020-05-10)
In women and females of different species of laboratory animals, oestrogens stimulate the renin-angiotensin-aldosterone system (RAAS) by increasing tissue and circulating levels of angiotensinogen and renin during the preovulatory period. Progesterone and cortisol compete with aldosterone for mineralocorticoid receptors, which
Resveratrol attenuates iron-induced toxicity in a chronic post-treatment paradigm in Caenorhabditis elegans
Free Radical Research, 52(9), 939-951 (2018)
Electrochemical and DFT study of the reduction of substituted phenanthrolines
Polyhedron, 122, 147-154 (2017)
Central Role of Phenanthroline Mono-N-oxide in the Decomposition Reactions of Tris (1, 10-phenanthroline) iron (II) and-iron (III) Complexes
Inorganic Chemistry, 49(9), 3968-3970 (2010)
The transmodulation of HER2 and EGFR by substance P in breast cancer cells requires c-Src and metalloproteinase activation
PLoS ONE, 10(6), e0129661-e0129661 (2015)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门