P7045
苯乙双胍 盐酸盐
analytical standard
别名:
N-（2-苯乙基）咪唑二碳酸二酰胺 单盐酸盐, 苯乙双胍
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H15N5 · HCl
化学文摘社编号:
分子量:
241.72
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
212-637-3
MDL number:
InChI key
YSUCWSWKRIOILX-UHFFFAOYSA-N
InChI
1S/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
SMILES string
Cl.NC(=N)NC(=N)NCCc1ccccc1
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。
盐酸苯乙双胍已用作测试化合物，以研究其在抑制卵巢癌细胞以及人类肝细胞癌细胞生长方面的抗肿瘤活性。
General description
盐酸苯乙双胍是一种双胍衍生物 ，具有抗糖尿病活性。
Relevance of the OCT1 transporter to the antineoplastic effect of biguanides
Segal D E, et al.
Biochemical and Biophysical Research Communications, 414(4), 694-699 (2011)
Energy metabolism determines the sensitivity of human hepatocellular carcinoma cells to mitochondrial inhibitors and biguanide drugs
Hsu C-C, et al.
Oncology Reports, 34(3), 1620-1628 (2015)
Kevin R W Ngoei et al.
Cell chemical biology, 25(6), 728-737 (2018-04-17)
The AMP-activated protein kinase (AMPK) αβγ heterotrimer regulates cellular energy homeostasis with tissue-specific isoform distribution. Small-molecule activation of skeletal muscle α2β2 AMPK complexes may prove a valuable treatment strategy for type 2 diabetes and insulin resistance. Herein, we report the
Valentina R Garbarino et al.
Pharmacological research, 140, 21-32 (2018-11-14)
Poorly managed gestational diabetes can lead to severe complications for mother and child including fetal overgrowth, neonatal hypoglycemia and increased autism risk. Use of metformin to control it is relatively new and promising. Yet safety concerns regarding gestational metformin use
Mozhgan Sedigh-Ardekani et al.
Regulatory toxicology and pharmacology : RTP, 70(2), 514-518 (2014-09-10)
Lactic acidosis occurs in a number of clinical conditions, e.g. in surgeries, orthotopic liver transplant, and anesthetic agent administration, which has deleterious effects on the patient's survival. The most rational therapy for these patients, the sodium bicarbonate administration, cannot prevent
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持