O5879
奥硝唑
analytical standard
别名:
1-(3-氯-2-羟丙基)-2-甲基-5-硝基咪唑
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关于此项目
线性分子式:
C7H10N3O3Cl
化学文摘社编号:
分子量:
219.63
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
240-826-0
MDL number:
InChI key
IPWKIXLWTCNBKN-UHFFFAOYSA-N
InChI
1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3
SMILES string
Cc1ncc(n1CC(O)CCl)[N+]([O-])=O
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Application
奥硝唑已被用作超高效液相色谱-质谱联用（UHPLC）测定水产养殖组织样品中痕量奥硝唑的标准品。
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Fehmi Tabak et al.
Liver international : official journal of the International Association for the Study of the Liver, 23(5), 351-354 (2004-01-08)
Metronidazole and ornidazole, synthetic nitroimidazole derivatives, are used in the treatment of infections caused by anaerobic bacteria and protozoa. The drugs are well tolerated and serious side effects are very rarely encountered. Hepatotoxicity is a rare side effect and hitherto
Alina Pyka-Pająk et al.
Molecules (Basel, Switzerland), 24(17) (2019-09-05)
The aim of this study was to assess the lipophilicity of selected antiparasitic, antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) by means of reversed phase-thin layer chromatography (RP-TLC) as well by using Soczewiński-Wachtmeister's and J. Ościk's equations. The lipophilicity parameters of
Nathalie Mahé et al.
Journal of pharmaceutical sciences, 100(6), 2258-2266 (2011-01-20)
The solid-state properties of antiprotozoal ternidazole (3-(2-methyl-5-nitroimidazol-1-yl)-propan-1-ol) have been studied. Crystals are triclinic in the temperature interval between 100 and 333 K (melting point) with two different molecular conformations present in the asymmetric unit (Z' = 2) and two of
Subhash S Vaghani et al.
Carbohydrate research, 347(1), 76-82 (2011-11-22)
In the present study, carboxymethyl chitosan was prepared from chitosan, crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for colon targeted drug delivery of ornidazole. Ornidazole was incorporated at the time of crosslinking of carboxymethyl chitosan. The
Kriti Shivhare et al.
International journal of biological macromolecules, 106, 775-783 (2017-08-19)
Molecular self-assembly of biodegradable amphiphilic polymers allows rational design of biocompatible nanomaterials for drug delivery. Use of substituted polysaccharides for such applications offers the ease of design and synthesis, and provides higher biofunctionality and biocompatibility to nanomaterials. The present work
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