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Merck
CN

O1002

Sigma-Aldrich

苯唑西林 钠盐 一水合物

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线性分子式:
C19H18N3O5SNa · H2O
CAS号:
分子量:
441.43
Beilstein:
4287093
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

形式

powder

质量水平

溶解性

water: 50-52 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

应用

diagnostic assay manufacturing
hematology
histology

储存温度

2-8°C

SMILES字符串

[Na+].[H]O[H].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c3c(C)onc3-c4ccccc4)C([O-])=O

InChI

1S/C19H19N3O5S.Na.H2O/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22;;/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key

ZVIYWUUZWWBNMB-VICXVTCVSA-M

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应用

Oxacillin sodium salt monohydrate has been used in penicillin (PEN) standards. In turbidimetric method, oxacillin sodium salt monohydrate has been used in the medium with antibiotic.

生化/生理作用

Oxacillin and its derivatives are released through urine with the help of glomerular filtration and tubular secretion. It can be used in nursing mothers. Oxacillin is used in the treatment of methicillin-susceptible S. aureus (MSSA) infections. It shows resistance to penicillinase.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品

分析证书(COA)

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访问文档库

Drugs and Lactation Database (LactMed) (2006)
The Washington Manual Infectious Diseases Subspecialty Consult, 352-352 (2005)
An easy-to-use, rapid and inexpensive method to determine methicillin resistance in Staphylococcus aureus.
Gocmen JS, et al.
Journal of Clinical and Experimental Investigations, 7(3), 225-251 (2016)
Nancy Tawil et al.
Biosensors & bioelectronics, 49, 334-340 (2013-06-26)
Two hundred fifty Staphylococcus aureus clinical isolates were studied to determine their susceptibilities to β-lactam antibiotics. Among these isolates, 16 were methicillin-sensitive S. aureus (MSSA), 207 were methicillin-resistant S. aureus (MRSA) and 27 were borderline oxacillin-resistant S. aureus (BORSA). Currently
Galoz Kaneti et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(12), 4834-4843 (2013-08-24)
In previous studies, the oligo-acyl-lysyl (OAK) C12(ω7)K-β12 added to cultures of gram-positive bacteria exerted a bacteriostatic activity that was associated with membrane depolarization, even at high concentrations. Here, we report that multidrug-resistant Staphylococcus aureus strains, unlike other gram-positive species, have

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