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O0200000

乌本苷

Name: 乌本苷
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

乌本苷八水合物, 1β,3β,5β,11α,14,19-Hexahydroxycard-20（22）-烯醇内酯-3-（6-脱氧-α-L-甘露糖苷）, G-毒毛花苷, 乌本苷

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关于此项目

经验公式（希尔记法）:

C₂₉H₄₄O₁₂ · 8H₂O

化学文摘社编号:

11018-89-6

分子量:

728.77

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329818827

MDL number:

MFCD00149240

Beilstein/REAXYS Number:

101712

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属性

grade

pharmaceutical primary standard

API family

ouabain

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.O.O.O.O.O.C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-;;;;;;;;/m0......../s1

InChI key

TYBARJRCFHUHSN-DMJRSANLSA-N

说明

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。

Application

哇巴因EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Packaging

本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。

Other Notes

可能适用相应的销售限制。

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pictograms

GHS06,GHS08

signalword

Danger

hcodes

H300,H331,H373

pcodes

P260 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P314

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 3 Inhalation - STOT RE 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

法规信息

危险化学品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Effect of bafilomycin and NAADP on membrane-associated ATPases and respiration of isolated mitochondria of the murine Nemeth-Kellner lymphoma.

V Hreniukh et al.

Cell biochemistry and function, 34(8), 579-587 (2016-11-20)

The goal of the study was to estimate the effect of a selective V-type H+ -ATPase inhibitor bafilomycin A1 and nicotinic acid adenine dinucleotide phosphate (NAADP) on energetic processes in NK/Ly cell by directly measuring the respiration of isolated mitochondria

Alterations of Na+/K+-ATPase, cholinergic and antioxidant enzymes activity by protocatechuic acid in cadmium-induced neurotoxicity and oxidative stress in Wistar rats.

Stephen A Adefegha et al.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 559-568 (2016-10-25)

This study assessed the possible protective mechanisms of protocatechuic acid (PCA) against cadmium (Cd)-induced oxidative stress and neurotoxicity in rats. Male wistar strain rats weighing between 150-160g were purchased and acclimatized for two weeks. The rats were divided into seven

Endocytic recycling of Na+ -K+ -Cl- cotransporter type 2: importance of exon 4.

Andrée-Anne Marcoux et al.

The Journal of physiology, 597(16), 4263-4276 (2019-06-20)

Na+ -K+ -Cl- cotransporter type 2 (NKCC2) is a 27-exon membrane protein that is expressed in the thick ascending limb (TAL) of Henle where it is involved in reabsorption of the ultrafiltered NaCl load. It comes as three splice variants

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货号	GTIN
O0200000	04061833813461