所有图片(2)
别名:
3β-羟基-5-胆甾烯, 5-胆甾烯-3β-醇
经验公式（希尔记法）:
C27H46O
CAS号:
分子量:
386.65
Beilstein:
1915888
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
推荐产品
等级
certified reference material
质量水平
包装
pkg of 2 g
制造商/商品名称
NIST®
bp
360 °C (lit.)
mp
147-149 °C (lit.)
密度
1.067 g/mL at 25 °C (lit.)
应用
clinical research
clinical testing
格式
neat
SMILES字符串
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key
HVYWMOMLDIMFJA-DPAQBDIFSA-N
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一般描述
This Standard Reference Material (SRM) is certified as a chemical of known purity. It is intended primarily for use in the calibration and standardization of procedures for the determination of cholesterol in research samples and for routine evaluations of daily working standards used in these procedures. A unit of SRM 911c consists of 2 g of material. For more information, please refer to the SDS and COA.
SRM 911C_cert
SRM 911C_SDS
SRM 911C_cert
SRM 911C_SDS
应用
- Estrone-mediated Improvements in Endothelial Function: Recent research has demonstrated how estrone treatment can lower ROS and NOX4 levels, significantly improving endothelial function in ovariectomized Wistar rats. This study utilized cholesterol as a critical component in understanding hormonal effects on vascular health, providing valuable insights for cardiovascular disease treatment strategies (Oliveira et al., 2024).
- Nephrotic Syndrome Case Study in Polycythemia Vera: Cholesterol plays a significant role in a case study of IgA nephropathy presenting as nephrotic syndrome in polycythemia vera. This research underscores the importance of cholesterol management in complex clinical scenarios, enhancing our understanding of kidney diseases linked with abnormal cholesterol metabolism (Rajasekar et al., 2024).
- Community Health Impact over a Decade: An extensive study over ten years has reviewed men′s health events in a socioeconomically diverse U.S. city, analyzing the impact of community-based interventions on health outcomes where cholesterol management was a key focus. The findings contribute to public health strategies aimed at improving population-wide cardiovascular health (Tinsley et al., 2024).
- Familial Hypercholesterolemia Complexities: A detailed case study addresses the complexities of managing familial hypercholesterolemia, discussing diagnostic and therapeutic approaches. The study highlights cholesterol′s central role in developing treatment protocols that can mitigate the risks associated with this genetic disorder (Rasheed et al., 2024).
- Cardiometabolic Markers and Fetal Growth: Research examining the association between maternal cardiometabolic markers, including cholesterol, and fetal growth in non-complicated pregnancies provides insights into prenatal care. The study suggests that managing cholesterol levels could influence fetal development outcomes, emphasizing the importance of maternal health monitoring (Omaña-Guzmán et al., 2024).
生化/生理作用
所有生物膜的主要成分；总脑脂质中约25%为胆固醇。
其他说明
Certified for the analytes listed below.
Cholestrol
See certificate for values and more details at nist.gov/SRM.
Cholestrol
See certificate for values and more details at nist.gov/SRM.
法律信息
NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Determination of total and esterified cholesterol in serum.
Sobel C and Fernandez A.
Clinical Chemistry, 12(11), 739-747 (1966)
Enzymatic determination of total serum cholesterol.
C C Allain et al.
Clinical chemistry, 20(4), 470-475 (1974-04-01)
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