推荐产品
等级
analytical standard
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
221-223 °C (lit.)
应用
food and beverages
格式
neat
储存温度
2-8°C
SMILES字符串
O.Cl.COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34
InChI
1S/C22H23NO7.ClH.H2O/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H;1H2/t17-,18+;;/m1../s1
InChI key
ZYGSNVAGWKWKKI-WCRQIBMVSA-N
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应用
Noscapine hydrochloride hydrate may be used as a reference standard in the determination of noscapine hydrochloride in the synthetic binary mixtures like chlorpheniramine-noscapine and chlorpheniramine-guaiphenesin using derivative spectrophotometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral - STOT SE 3
靶器官
Central nervous system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
Patricia López et al.
Food chemistry, 242, 443-450 (2017-10-19)
A straightforward method to determine the content of six opium alkaloids (morphine, codeine, thebaine, noscapine, papaverine and narceine) in poppy seeds and bakery products was developed and validated down to a limit of quantification (LOQ) of 0.1mg/kg. The method was
Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry.
Pappano B N, et al.
Talanta, 44(4), 633-639 (1997)
Ana Amaral et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Endometrosis is a reproductive pathology that is responsible for mare infertility. Our recent studies have focused on the involvement of neutrophil extracellular traps enzymes, such as elastase (ELA), in the development of equine endometrosis. Noscapine (NOSC) is an alkaloid derived
Ana Amaral et al.
Life (Basel, Switzerland), 11(10) (2021-10-24)
Cathepsin G (CAT) is a protease released by neutrophils when forming neutrophil extracellular traps that was already associated with inducing type I collagen (COL1) in equine endometrium in vitro. Endometrosis is a fibrotic condition mainly characterized by COL1 deposition in
Srinivasa M Sammeta et al.
Pharmaceutical development and technology, 20(2), 169-175 (2013-11-14)
The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches. Different combinations of co-solvents, which were selected on the basis of high-throughput solubility screening, were
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