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About This Item
经验公式（希尔记法）:
C17H27NO4
CAS号:
分子量:
309.40
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12
InChI
1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1
InChI key
VWPOSFSPZNDTMJ-UCWKZMIHSA-N
基因信息
human ... ADRB1(153) , ADRB2(154)
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应用
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
生化/生理作用
β-肾上腺素阻断剂
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
Priya Chockalingam et al.
Journal of the American College of Cardiology, 60(20), 2092-2099 (2012-10-23)
The purpose of this study was to compare the efficacy of beta-blockers in congenital long QT syndrome (LQTS). Beta-blockers are the mainstay in managing LQTS. Studies comparing the efficacy of commonly used beta-blockers are lacking, and clinicians generally assume they
Sarah Maud Fischer et al.
International journal of pharmaceutics, 422(1-2), 52-58 (2011-10-27)
The compatibility of fasted state simulated intestinal fluid (FaSSIF) in drug permeation studies employing the phospholipid vesicle-based permeation assay (PVPA) model was confirmed by a set of different integrity indicators. Neither calcein permeability nor electrical resistance were found significantly changed
Sarah Maud Fischer et al.
The Journal of pharmacy and pharmacology, 63(8), 1022-1030 (2011-07-02)
The aim of this study was to determine the influence of nonionic surfactants on drug permeability using the phospholipid vesicle-based permeation assay (PVPA), which excludes other than trans-membrane diffusion pathways. Barrier integrity was monitored both by electrical resistance and permeability
Wai Gin Lee et al.
Metabolism: clinical and experimental, 61(11), 1547-1553 (2012-05-09)
Elevated resting energy expenditure (REE) is seen in liver cirrhosis and is associated with reduced transplant-free survival. Non-selective β-blockers reduce REE in acute hypermetabolic conditions. We examined whether non-selective β-blockers reduce REE in patients with stable liver cirrhosis. Twenty-two stable
Vishantie Dostal et al.
Genetics, 186(3), 857-866 (2010-09-02)
Epidemiological studies have reported that coffee and/or caffeine consumption may reduce Alzheimer's disease (AD) risk. We found that coffee extracts can similarly protect against β-amyloid peptide (Aβ) toxicity in a transgenic Caenorhabditis elegans Alzheimer's disease model. The primary protective component(s)
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